Bargiotas Panagiotis, Muellner Julia, Schuepbach W M Michael, Bassetti Claudio L
Department of Neurology, University Hospital (Inselspital) and University of Bern, Freiburgstrasse 18, 3010, Bern, Switzerland.
BMC Neurol. 2017 Jul 18;17(1):137. doi: 10.1186/s12883-017-0916-0.
Parasomnia overlap disorder (POD) is a distinct parasomnia and characterized by concomitant manifestation of rapid-eye-movement (REM)- and non-REM (NREM)-parasomnias. Although not uncommon among patients with Parkinson's disease, POD is often under-investigated.
This is the first report of patients with PD and features of POD that underwent deep brain stimulation. Our patients exhibited different outcomes of POD features after subthalamic deep brain stimulation.
We expect that the reporting of these first patients will open the discussion about the need for more detailed and broad-spectrum assessments regarding parasomnias in PD patients that undergo deep brain stimulation. The implications of our observations are both clinical and neurobiological.
异态睡眠重叠障碍（POD）是一种独特的异态睡眠，其特征是快速眼动（REM）和非快速眼动（NREM）异态睡眠同时出现。虽然在帕金森病患者中并不罕见，但POD常常未得到充分研究。
这是首例患有帕金森病且具有POD特征并接受脑深部电刺激的患者报告。我们的患者在丘脑底核脑深部电刺激后呈现出不同的POD特征结果。
我们预计，这些首例患者的报告将开启关于对接受脑深部电刺激的帕金森病患者的异态睡眠进行更详细和广谱评估必要性的讨论。我们观察结果的意义兼具临床和神经生物学方面。
