Yu Fang, Greimel Susan, Kelly Kaitlin, Wyman Jean F
University of Minnesota School of Nursing, Minneapolis, MN, United States.
Appl Nurs Res. 2017 Aug;36:77-80. doi: 10.1016/j.apnr.2017.05.002. Epub 2017 May 21.
Alzheimer’s disease (AD) affects 5.2 million Americans in 2016 and this number will increase to 14.7 million by 2050. Unfortunately, AD cannot yet be prevented, slowed, or cured. Aerobic exercise is potentially therapeutic for Alzheimer’s disease (AD) as it favorably affects brain structure and function. A critical determinant in testing its effectiveness is optimal adherence to the exercise prescription. AD symptoms, particularly behavioral and psychological symptoms of dementia (BPSD), however, make exercise delivery and adherence challenging. The purpose of this paper is to discuss the strategies used for managing BPSD during exercise using a multiple case study design. Three cases with BPSD that met the eligibility criteria were selected from the FIT-AD Trial. The FIT-AD Trial is an ongoing randomized controlled trial that tests the effects of a 6-month moderate intensity aerobic exercise on cognition and hippocampal volume in community-dwelling persons with AD. The cases included: a 77-year-old woman with mild AD, a 79-year-old woman with mild AD, and a 69-year-old man with moderate AD. The participants exhibited anxiety, repetitive questioning, irritability, hostility, extreme distractedness, resistance to instruction, and hoarding during exercise. The symptoms were effectively addressed using person-centered strategies such as routine schedules, reassurance, timely communications, distraction, small rewards, rephrasing, immediate answers, selective withdrawal from conversations that were hostile, step by step instructions, building on rapport and relationship with staff, and affirmation. They achieved 83.3%–100% attendance and 52.8%–81.7% session adherence, respectively. In conclusion, individualized strategies for BPSD are necessary to ensure optimal exercise adherence.
2016年,阿尔茨海默病(AD)影响了520万美国人,到2050年这一数字将增至1470万。不幸的是,AD目前仍无法预防、延缓或治愈。有氧运动对阿尔茨海默病(AD)具有潜在治疗作用,因为它对大脑结构和功能有积极影响。测试其有效性的一个关键决定因素是对运动处方的最佳依从性。然而,AD症状,尤其是痴呆的行为和心理症状(BPSD),使得运动实施和依从性具有挑战性。本文旨在通过多案例研究设计,探讨在运动过程中管理BPSD的策略。从FIT-AD试验中选取了3例符合入选标准的BPSD患者。FIT-AD试验是一项正在进行的随机对照试验,旨在测试为期6个月的中等强度有氧运动对社区居住的AD患者认知和海马体积的影响。这些案例包括:一名患有轻度AD的77岁女性、一名患有轻度AD的79岁女性和一名患有中度AD的69岁男性。参与者在运动过程中表现出焦虑、反复提问、易怒、敌意、极度分心、抗拒指令和囤积行为。通过以患者为中心的策略,如常规日程安排、安抚、及时沟通、分散注意力、小奖励、重新措辞、立即回答、选择性退出敌对对话、逐步指导、建立与工作人员的融洽关系和肯定,有效地解决了这些症状。他们的出勤率分别达到了83.3% - 100%,课程依从率分别达到了52.8% - 81.7%。总之,针对BPSD的个性化策略对于确保最佳运动依从性是必要的。