Moss Heather E
Department of Ophthalmology, Stanford University, Palo Alto, CA, USA.
Department of Neurology & Neuroscience, Stanford University, Stanford, CA, USA.
Eye Brain. 2017 Jun 29;9:13-21. doi: 10.2147/EB.S140481. eCollection 2017.
Multiple sclerosis (MS) is associated with vision changes both due to MS effects on visual pathways and due to medication effects on the visual pathways. Distinguishing the causes of vision change are critical to appropriate diagnosis and management. The incidence, presentation, and treatment of fingolimod-associated macular edema, alemtuzumab-associated thyroid orbitopathy, and progressive multifocal leukoencephalopathy in MS patients are reviewed. Evidence for beneficial effects of acute, chronic, and symptomatic MS medications on vision is presented.
多发性硬化症（MS）与视力变化有关，这既归因于MS对视神经通路的影响，也归因于药物对视神经通路的影响。区分视力变化的原因对于正确的诊断和治疗至关重要。本文综述了MS患者中与芬戈莫德相关的黄斑水肿、与阿仑单抗相关的甲状腺眼眶病以及进行性多灶性白质脑病的发病率、表现和治疗。还介绍了急性、慢性和对症MS药物对视力有益影响的证据。
