Shachar Shlomit Strulov, Muss Hyman B
Lineberger Comprehensive Cancer Center, Department of Medicine, University of North Carolina, Chapel Hill, NC, USA.
Division of Oncology, Rambam Health Care Campus, Haifa, Israel.
NPJ Breast Cancer. 2016 Apr 27;2:16011. doi: 10.1038/npjbcancer.2016.11. eCollection 2016.
Internet tools have become a great aid in the daily practice of physicians who treat breast cancer patients. In cancer care there are frequent and important intersections where major decisions need to be made; these include (1) whether or not to give chemotherapy; (2) how much toxicity to expect, and (3) the life expectancy of the patient, considering non-breast cancer comorbidities. These decisions can be made more accurately using calculators based on data sets of thousands of patients as opposed to physician intuition. Such tools also help patients and caregivers in optimal decision making, as they estimate the absolute benefits and risks of treatment. In this perspective we describe selected internet sites that are useful across several domains of care, including the potential benefits of different adjuvant regimens for early breast cancer, prognosis after neoadjuvant therapy, prognosis for ductal carcinoma , and toxicity and life expectancy estimates. We review the variables required to use the tools, the results obtained, the methods of validation, and the advantages and disadvantages of each tool.
互联网工具已成为治疗乳腺癌患者的医生日常工作中的一大助力。在癌症治疗中,存在频繁且重要的交叉点,需要做出重大决策;这些决策包括:(1)是否进行化疗;(2)预期的毒性程度;以及(3)考虑到非乳腺癌合并症的患者预期寿命。与医生的直觉相比,使用基于数千名患者数据集的计算器可以更准确地做出这些决策。此类工具还能帮助患者和护理人员做出最佳决策,因为它们可以估算治疗的绝对益处和风险。从这个角度出发,我们描述了一些在多个护理领域都有用的互联网网站,包括不同辅助治疗方案对早期乳腺癌的潜在益处、新辅助治疗后的预后、导管癌的预后以及毒性和预期寿命估算。我们回顾了使用这些工具所需的变量、获得的结果、验证方法以及每个工具的优缺点。