Licona-Enriquez Jesus David, Delgado-de la Mora Jesus, Paddock Christopher D, Ramirez-Rodriguez Carlos Arturo, Candia-Plata María Del Carmen, Hernández Gerardo Álvarez
Department of Medicine and Health Sciences, University of Sonora, Hermosillo, Mexico.
Rickettsial Zoonoses Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia.
Am J Trop Med Hyg. 2017 Sep;97(3):795-798. doi: 10.4269/ajtmh.16-0917. Epub 2017 Jul 19.
We present a series of four pregnant women with Rocky Mountain spotted fever (RMSF) that occurred in Sonora, Mexico, during 2015-2016. Confirmatory diagnoses were made by polymerase chain reaction or serological reactivity to antigens of by using an indirect immunofluorescence antibody assay. Each patient presented with fever and petechial rash and was treated successfully with doxycycline. Each of the women and one full-term infant delivered at 36 weeks gestation survived the infection. Three of the patients in their first trimester of pregnancy suffered spontaneous abortions. RMSF should be suspected in any pregnant woman presenting with fever, malaise and rash in regions where is endemic.
我们报告了2015年至2016年期间在墨西哥索诺拉州发生的一系列4例落基山斑疹热(RMSF)孕妇病例。通过聚合酶链反应或使用间接免疫荧光抗体试验对抗原的血清学反应性进行确诊。每位患者均出现发热和瘀点性皮疹,并接受强力霉素成功治疗。每位女性及一名在妊娠36周时足月分娩的婴儿均在感染中存活。三名处于妊娠早期的患者发生了自然流产。在落基山斑疹热流行地区,任何出现发热、不适和皮疹的孕妇都应怀疑感染该病。