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落基山斑疹热与妊娠:来自墨西哥索诺拉州的4例病例

Rocky Mountain Spotted Fever and Pregnancy: Four Cases from Sonora, Mexico.

作者信息

Licona-Enriquez Jesus David, Delgado-de la Mora Jesus, Paddock Christopher D, Ramirez-Rodriguez Carlos Arturo, Candia-Plata María Del Carmen, Hernández Gerardo Álvarez

机构信息

Department of Medicine and Health Sciences, University of Sonora, Hermosillo, Mexico.

Rickettsial Zoonoses Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia.

出版信息

Am J Trop Med Hyg. 2017 Sep;97(3):795-798. doi: 10.4269/ajtmh.16-0917. Epub 2017 Jul 19.

DOI:10.4269/ajtmh.16-0917
PMID:28722584
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5590584/
Abstract

We present a series of four pregnant women with Rocky Mountain spotted fever (RMSF) that occurred in Sonora, Mexico, during 2015-2016. Confirmatory diagnoses were made by polymerase chain reaction or serological reactivity to antigens of by using an indirect immunofluorescence antibody assay. Each patient presented with fever and petechial rash and was treated successfully with doxycycline. Each of the women and one full-term infant delivered at 36 weeks gestation survived the infection. Three of the patients in their first trimester of pregnancy suffered spontaneous abortions. RMSF should be suspected in any pregnant woman presenting with fever, malaise and rash in regions where is endemic.

摘要

我们报告了2015年至2016年期间在墨西哥索诺拉州发生的一系列4例落基山斑疹热(RMSF)孕妇病例。通过聚合酶链反应或使用间接免疫荧光抗体试验对抗原的血清学反应性进行确诊。每位患者均出现发热和瘀点性皮疹,并接受强力霉素成功治疗。每位女性及一名在妊娠36周时足月分娩的婴儿均在感染中存活。三名处于妊娠早期的患者发生了自然流产。在落基山斑疹热流行地区,任何出现发热、不适和皮疹的孕妇都应怀疑感染该病。

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本文引用的文献

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Diagnosis and Management of Tickborne Rickettsial Diseases: Rocky Mountain Spotted Fever and Other Spotted Fever Group Rickettsioses, Ehrlichioses, and Anaplasmosis - United States.蜱传斑疹伤寒立克次体病的诊断和治疗:落矶山斑点热和其他斑点热群立克次体病、埃立克体病和无形体病 - 美国。
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No visible dental staining in children treated with doxycycline for suspected Rocky Mountain Spotted Fever.用多西环素治疗疑似落基山斑疹热的儿童未出现明显的牙齿染色。
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Rocky mountain spotted fever characterization and comparison to similar illnesses in a highly endemic area-Arizona, 2002-2011.落基山斑疹热的特征及与高流行地区(亚利桑那州,2002 - 2011年)类似疾病的比较
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Pregnancy outcome in relation to treatment of murine typhus and scrub typhus infection: a fever cohort and a case series analysis.与鼠型斑疹伤寒和恙虫病感染治疗相关的妊娠结局:发热队列研究和病例系列分析
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[Rocky Mountain spotted fever, a forgotten epidemic].[落基山斑疹热,一种被遗忘的流行病]
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