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血友病患者同期双侧全膝关节置换术:是否推荐?

Simultaneous bilateral total knee arthroplasty in hemophilia: is it recommended?

作者信息

Rodriguez-Merchan E Carlos

机构信息

a Department of Orthopedic Surgery , La Paz University Hospital , Madrid , Spain.

出版信息

Expert Rev Hematol. 2017 Oct;10(10):847-851. doi: 10.1080/17474086.2017.1358084. Epub 2017 Jul 31.

Abstract

Simultaneous bilateral total knee arthroplasty (TKA) is a potentially cost-saving manner of caring for patients with hemophilia who have bilateral symptomatic hemophilic knee arthropathy. Because factor VIII is used only once in bilateral TKA, it is performed in hemophilia to reduce costs. Areas covered: This article reviews the potential role of simultaneous bilateral TKA in patients with hemophilia. Expert commentary: Although two recent reports have mentioned the benefits of simultaneous bilateral TKA in patients with hemophilia, the data are still scant and preliminary. The two systematic reviews and the meta-analyses on bilateral TKA in patients without hemophilia have shown that there are more complications with bilateral TKA than with unilateral TKA. This article calls the potential risks of this technique to the attention of hemophilia specialists. The current use of simultaneous bilateral TKA in patients with hemophilia is unadvised, and raising false expectations in these patients should be avoided. Prospective studies in the specific field of TKA in patients with hemophilia are needed.

摘要

同期双侧全膝关节置换术(TKA)是一种可能节省成本的治疗血友病合并双侧症状性血友病性膝关节病患者的方式。由于在双侧TKA中仅使用一次凝血因子VIII,因此在血友病患者中进行该手术以降低成本。涵盖领域:本文综述了同期双侧TKA在血友病患者中的潜在作用。专家评论:尽管最近的两份报告提到了同期双侧TKA对血友病患者的益处,但数据仍然稀少且初步。两项关于非血友病患者双侧TKA的系统评价和荟萃分析表明,双侧TKA比单侧TKA有更多并发症。本文提请血友病专家注意该技术的潜在风险。目前不建议在血友病患者中使用同期双侧TKA,应避免在这些患者中产生不切实际的期望。需要在血友病患者TKA的特定领域进行前瞻性研究。

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