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血友病性关节病同期全髋关节和全膝关节置换术:5例病例系列

Simultaneous total hip and knee arthroplasties in hemophilic arthropathy: series of 5 cases.

作者信息

Bakan Özgür Mert, Vahabi Arman, Kaya Biçer Elcil, Şahin Fahri, Kavaklı Kaan, Aydoğdu Semih

机构信息

Department of Orthopedics and Traumatology, Mardin Park Private Hospital, Mardin, Türkiye.

Department of Orthopedics and Traumatology, Ege University School of Medicine, Izmir, Türkiye.

出版信息

Acta Orthop Traumatol Turc. 2024 Dec 31;58(6):336-340. doi: 10.5152/j.aott.2024.24044.

DOI:10.5152/j.aott.2024.24044
PMID:39876488
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11740237/
Abstract

OBJECTIVE

This study aimed to compare preoperative and postoperative measures in haemophiliacs who had simultaneous total hip and knee arthroplasties.

METHODS

A retrospective database search identified five patients with severe factor 8 deficiencies who underwent simultaneous hip and knee joint replacement surgery between 2002-2018. Preoperative and postoperative evaluations included Harris Hip Score (HHS), Knee Society Score (KSS), Knee Injury and Osteoarthritis Outcome Score (KOOS), range of motion, flexion contracture (FC), Visual Analog Scale (VAS), hip-knee angle, and leg length discrepancy.

RESULTS

The mean age of the patients was 50.8 years, with a mean follow-up duration of 60 months. Preoperative knee ROM was 55 degrees, improving to 73.8 degrees postoperatively. Preoperative knee FC was 13.7 degrees, improving to 10 degrees postoperatively. HHS increased from 45.6 to 75.7, KSS increased from 36 to 69.3, and KOOS total score increased from 34.4 to 82.7. VAS scores decreased from 6.3 to 1.3. One patient experienced prolonged bleeding and subsequent complications, while the others showed significant improvements.

CONCLUSION

Simultaneous hip and knee arthroplasties in hemophiliacs may provide benefits in terms of physical and functional gains. However, the increased risk of complications necessitates careful patient selection. For patients with comorbidities, staged surgeries may be advisable to avoid potential complications.

LEVEL OF EVIDENCE

Level IV, Therapeutic study.

摘要

目的

本研究旨在比较同时进行全髋关节和膝关节置换术的血友病患者术前和术后的各项指标。

方法

通过回顾性数据库检索,确定了5例在2002年至2018年间接受同期髋关节和膝关节置换手术的重度Ⅷ因子缺乏患者。术前和术后评估包括Harris髋关节评分(HHS)、膝关节协会评分(KSS)、膝关节损伤和骨关节炎疗效评分(KOOS)、活动范围、屈曲挛缩(FC)、视觉模拟量表(VAS)、髋膝角和肢体长度差异。

结果

患者的平均年龄为50.8岁,平均随访时间为60个月。术前膝关节活动范围为55度,术后改善至73.8度。术前膝关节FC为13.7度,术后改善至10度。HHS从45.6提高到75.7,KSS从36提高到69.3,KOOS总分从34.4提高到82.7。VAS评分从6.3降至1.3。1例患者出现出血时间延长及随后的并发症,而其他患者均有显著改善。

结论

血友病患者同期进行髋关节和膝关节置换术在身体和功能改善方面可能有益。然而,并发症风险增加需要仔细选择患者。对于有合并症的患者,分期手术可能是明智的,以避免潜在并发症。

证据水平

IV级,治疗性研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cdab/11740237/6af573cbe910/aott-58-6-336_f003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cdab/11740237/6d542dd6a444/aott-58-6-336_f001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cdab/11740237/575bbd438b29/aott-58-6-336_f002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cdab/11740237/6af573cbe910/aott-58-6-336_f003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cdab/11740237/6d542dd6a444/aott-58-6-336_f001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cdab/11740237/575bbd438b29/aott-58-6-336_f002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cdab/11740237/6af573cbe910/aott-58-6-336_f003.jpg

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本文引用的文献

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Primary total knee arthroplasty in hemophilic arthropathy.血友病性关节病的初次全膝关节置换术。
EFORT Open Rev. 2023 Nov 1;8(11):830-840. doi: 10.1530/EOR-23-0101.
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Cost analysis of staged versus simultaneous bilateral total knee and hip arthroplasty using a propensity score matching.采用倾向评分匹配的分期与同期双侧全膝关节和髋关节置换术的成本分析。
BMJ Open. 2021 Mar 2;11(3):e041147. doi: 10.1136/bmjopen-2020-041147.
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One-staged combined hip and knee arthroplasty: retrospective comparative study at mid-term follow-up.一期同期髋关节与膝关节置换术:中期随访回顾性对比研究。
J Orthop Surg Res. 2019 Sep 5;14(1):301. doi: 10.1186/s13018-019-1337-0.
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Comparison of 90-Day Complication Rates and Cost Between Single and Multiple Joint Procedures for End-Stage Arthropathy in Patients with Hemophilia.血友病终末期关节病患者单关节与多关节手术90天并发症发生率及费用的比较。
JB JS Open Access. 2018 Oct 23;3(4):e0026. doi: 10.2106/JBJS.OA.18.00026. eCollection 2018 Dec 20.
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Total Hip Arthroplasty in Hemophilia Patients: A Mid-term to Long-term Follow-up.血友病患者的全髋关节置换术:中期至长期随访
Orthop Surg. 2017 Nov;9(4):359-364. doi: 10.1111/os.12354.
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Simultaneous bilateral total knee arthroplasty in hemophilia: is it recommended?血友病患者同期双侧全膝关节置换术:是否推荐?
Expert Rev Hematol. 2017 Oct;10(10):847-851. doi: 10.1080/17474086.2017.1358084. Epub 2017 Jul 31.
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Simultaneous bilateral total knee arthroplasty in patients with haemophilia: a safe and cost-effective procedure?血友病患者同期双侧全膝关节置换术:一种安全且具有成本效益的手术?
Haemophilia. 2016 Mar;22(2):303-307. doi: 10.1111/hae.12832. Epub 2015 Nov 4.
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Simultaneous bilateral total knee arthroplasty in severe hemophilia: a retrospective cost-effectiveness analysis.重度血友病患者同期双侧全膝关节置换术:一项回顾性成本效益分析
Orthop Traumatol Surg Res. 2015 Apr;101(2):147-50. doi: 10.1016/j.otsr.2014.12.010. Epub 2015 Feb 14.
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