Patel Kanika, Patel Dinesh Kumar
Jubilant Life Sciences, Noida, Uttar Pradesh, 201301, India.
Department of Pharmacy, Galgotias University, Greater Noida, 203201, Uttar Pradesh, India.
J Tradit Complement Med. 2016 Dec 10;7(3):360-366. doi: 10.1016/j.jtcme.2016.11.003. eCollection 2017 Jul.
Herbal medicines have been played an important role in the human civilization since very ancient time as a food, cloth, medicine and other aspects. Some of the important drugs in the modern medicine were derived from the natural sources such as aspirin, digitalis, quinine, vincristine, vinblastine etc. Hispidulin (4', 5, 7-trihydroxy-6-methoxyflavone) is a flavones derivative found in plant such as , Artemisia and Salvia species. Hispidulin have antioxidant, antifungal, anti-inflammatory, antimutagenic, and antineoplastic properties. So far, various analytical methods have been investigated and developed for detection of hispidulin in the plant materials. Productions of hispidulin through different tissue culture techniques have been also investigated. Present review summarized medicinal uses, pharmacological activities and analytical aspects of hispidulin. From the above mentioned aspects, we can conclude that, this review will be helpful to the researcher in the field of natural product for the development of novel molecule for the treatment of different disorders.
自古以来，草药在人类文明中就作为食物、布料、药物等方面发挥着重要作用。现代医学中的一些重要药物来源于天然物质，如阿司匹林、洋地黄、奎宁、长春新碱、长春碱等。滨蓟黄素（4',5,7-三羟基-6-甲氧基黄酮）是一种黄酮类衍生物，存在于植物如滨蓟、蒿属和鼠尾草属植物中。滨蓟黄素有抗氧化、抗真菌、抗炎、抗诱变和抗肿瘤特性。到目前为止，已经研究和开发了各种分析方法用于检测植物材料中的滨蓟黄素。通过不同组织培养技术生产滨蓟黄素也已得到研究。本综述总结了滨蓟黄素的药用、药理活性和分析方面。从上述方面可以得出结论，本综述将有助于天然产物领域的研究人员开发用于治疗不同疾病的新型分子。
