College of Food Science, South China Agricultural University, 483 Wushan Street, Tianhe District, Guangzhou 510642, China.
Food Funct. 2017 Aug 1;8(8):2836-2846. doi: 10.1039/c7fo00368d. Epub 2017 Jul 20.
Cocoa tea (Camellia ptilophylla Chang) is a naturally low caffeine-containing but gallocatechin gallate (GCG)-rich tea cultivar, though its biological activities have not been extensively explored. Herein, we evaluated the in vitro cellular antioxidant, methylglyoxal trapping, and anti-inflammatory activities of water extract of green tea from cocoa tea (CWE) and Yunnan Daye tea (Camellia sinensis) (YWE), and their predominant bioactive components GCG and epigallocatechin gallate (EGCG) for comparative purposes. Primarily, CWE exhibited a higher cellular antioxidant potential than YWE via a cellular antioxidant activity assay, while no significant difference was observed between GCG and EGCG. Moreover, CWE was more potent than YWE in the inhibitory effect on inflammatory responses in lipopolysaccharide-induced RAW 264.7 macrophages, including nitric oxide and interleukin-6 productions. Additionally, CWE showed comparable MGO trapping ability to YWE, although EGCG was more reactive with MGO than with GCG. This study suggested that cocoa tea would be a promising and potential functional beverage as a dietary antioxidant, methylglyoxal trapping, and anti-inflammatory agent.
可可茶（Camellia ptilophylla Chang）是一种天然低咖啡因但富含没食子儿茶素没食子酸酯（GCG）的茶品种，尽管其生物活性尚未得到广泛探索。在此，我们评估了可可茶（CWE）和云南大叶茶（Camellia sinensis）（YWE）的绿茶水提取物的体外细胞抗氧化、甲基乙二醛捕获和抗炎活性，以及它们的主要生物活性成分没食子儿茶素没食子酸酯（GCG）和表没食子儿茶素没食子酸酯（EGCG），以进行比较。首先，通过细胞抗氧化活性测定，CWE 表现出比 YWE 更高的细胞抗氧化潜力，而 GCG 和 EGCG 之间没有观察到显著差异。此外，CWE 在抑制脂多糖诱导的 RAW 264.7 巨噬细胞炎症反应方面比 YWE 更有效，包括一氧化氮和白细胞介素-6 的产生。此外，CWE 显示出与 YWE 相当的 MGO 捕获能力，尽管 EGCG 比 GCG 更能与 MGO 反应。本研究表明，可可茶作为一种膳食抗氧化剂、甲基乙二醛捕获剂和抗炎剂，将是一种很有前途和潜力的功能性饮料。
