Department of Anatomy, Faculty of Health Sciences, University of Pretoria, South Africa.
Food Funct. 2017 Dec 13;8(12):4601-4610. doi: 10.1039/c7fo01067b.
Ilex guayusa tea preparations are now commercially available as Runa tea. Little is known regarding the antioxidant and anti-inflammatory bioactivities of this tea. The I. guayusa teas had a total polyphenolic content between 54.39 and 67.23 mg GAE per g dry mass and peroxyl radical scavenging capacities between 1773.41 and 2019 μmol TE per g dry mass, nearly half of that for the Camellia sinensis teas. The I. guayusa teas afforded 60-80% protection from oxidative stress in the Caco-2 cellular antioxidant assay, comparable to the C. sinensis teas. The anti-inflammatory activity in lipopolysaccharide-stimulated RAW 264.7 cells of I. guayusa teas was similarly comparable to the C. sinensis teas with nitric oxide production reduced by 10-30%. Major compounds identified by mass spectrometry were the phenolic mono- and dicaffeoylquinic acid derivatives. I. guayusa teas are a good source of dietary phenolic compounds with cellular antioxidant and anti-inflammatory properties.
冬青属瓜哇茶制剂现已作为 Runa 茶商业化。关于这种茶的抗氧化和抗炎生物活性知之甚少。I. guayusa 茶的总多酚含量为每克干重 54.39 至 67.23 毫克 GAE，过氧自由基清除能力为每克干重 1773.41 至 2019 微摩尔 TE，接近一半的茶儿茶素茶。I. guayusa 茶在 Caco-2 细胞抗氧化测定中提供了 60-80%的氧化应激保护，与茶儿茶素茶相当。脂多糖刺激 RAW 264.7 细胞中 I. guayusa 茶的抗炎活性与茶儿茶素茶相当，一氧化氮生成减少 10-30%。通过质谱鉴定的主要化合物是酚类单和二咖啡酰奎宁酸衍生物。I. guayusa 茶是膳食酚类化合物的良好来源，具有细胞抗氧化和抗炎特性。
