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饮酒模式与老年人跌倒风险:一项前瞻性队列研究。

Patterns of alcohol consumption and risk of falls in older adults: a prospective cohort study.

机构信息

Department of Preventive Medicine and Public Health, School of Medicine, Universidad Autónoma de Madrid and Idipaz, Calle del Arzobispo Morcillo 4, 28029, Madrid, Spain.

CIBER of Epidemiology and Public Health (CIBERESP), Avenida de Monforte de Lemos 3-5, 28029, Madrid, Spain.

出版信息

Osteoporos Int. 2017 Nov;28(11):3143-3152. doi: 10.1007/s00198-017-4157-2. Epub 2017 Jul 19.

Abstract

UNLABELLED

Falls are a major health problem in older adults, but their relationship with alcohol consumption in this population remains unclear. In a cohort with 2170 older adults followed up for 3.3 years, both moderate drinking and the Mediterranean drinking pattern were associated with a lower risk of falls and injurious falls.

INTRODUCTION

This study aims to examine the association between certain patterns of alcohol consumption, including the Mediterranean drinking pattern (MDP), and the risk of falls in older adults.

METHODS

A prospective cohort with 2170 community-dwelling individuals aged ≥60 years was recruited in Spain in 2008-2010 and followed up through 2012. At baseline, participants reported alcohol consumption and, at the end of follow-up, their falls during the previous year. The MDP was defined as moderate alcohol consumption (threshold between moderate and heavy intake was 40 g/day for men and 24 g/day for women) with preference for wine and drinking only with meals. Analyses were conducted with negative binomial or logistic regression, as appropriate, and adjusted for the main confounders.

RESULTS

Compared with never drinkers, the number of falls was lower in moderate drinkers (incidence rate ratio (95% confidence interval), 0.79 (0.63-0.99)) and drinkers with MDP (0.73 (0.56-0.96)). Also, moderate drinkers and those with MDP showed a lower risk of ≥2 falls (odds ratio (95% confidence interval), 0.58 (0.38-0.88) and 0.56 (0.34-0.93), respectively) and of falls requiring medical care (0.67 (0.46-0.96) and 0.61 (0.39-0.96), respectively).

CONCLUSION

Both moderate drinking and the MDP were associated with a lower risk of falls and injurious falls in older adults. However, sound advice on alcohol consumption should balance risks and benefits.

摘要

目的

本研究旨在探讨特定饮酒模式(包括地中海饮酒模式)与老年人跌倒风险之间的关系。

方法

本研究为前瞻性队列研究,纳入了 2008-2010 年在西班牙参加的 2170 名年龄≥60 岁的社区居民,并随访至 2012 年。在基线时,参与者报告了他们的饮酒情况,在随访结束时,报告了他们在过去一年中发生的跌倒情况。地中海饮酒模式定义为适度饮酒(男性中度和重度饮酒的阈值为 40g/天,女性为 24g/天),偏好葡萄酒,并在进餐时饮酒。采用负二项或逻辑回归分析,根据主要混杂因素进行调整。

结果

与从不饮酒者相比,适度饮酒者(发生率比(95%置信区间),0.79(0.63-0.99))和地中海饮酒模式者(0.73(0.56-0.96))的跌倒次数较少。此外,适度饮酒者和地中海饮酒模式者发生≥2 次跌倒的风险较低(比值比(95%置信区间),0.58(0.38-0.88)和 0.56(0.34-0.93)),需要医疗护理的跌倒风险也较低(0.67(0.46-0.96)和 0.61(0.39-0.96))。

结论

适度饮酒和地中海饮酒模式均与老年人跌倒和伤害性跌倒的风险降低有关。然而,关于饮酒的合理建议应该权衡风险和益处。

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