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肥胖症患者接受减重手术后出现不明原因的腹痛。

Unexplained abdominal pain in morbidly obese patients after bariatric surgery.

机构信息

Department of Surgery, Onze Lieve Vrouwe Gasthuis, locatie West (Previously Sint Lucas Andreas Ziekenhuis, Amsterdam, the Netherlands), Amersterdam, the Netherlands.

Department of Surgery, Vrije Universiteit Medisch Centrum, Amsterdam, the Netherlands.

出版信息

Surg Obes Relat Dis. 2017 Oct;13(10):1743-1751. doi: 10.1016/j.soard.2017.05.027. Epub 2017 Jul 3.

Abstract

BACKGROUND

There is an overall complication rate of 6.3%-10% after bariatric surgery. After ruling out anatomic/physical causes, there is a substantial group of patients who develop unexplained postsurgical abdominal pain.

OBJECTIVES

To inventory the prevalence of unexplained abdominal pain after laparoscopic Roux-en-Y gastric bypass or laparoscopic sleeve gastrectomy and to determine predictive factors for unexplained abdominal pain.

SETTING

Obesity Center Amsterdam, Amsterdam, the Netherlands.

METHODS

A retrospective study in a prospective database was performed. Baseline characteristics and postoperative course were evaluated.

RESULTS

A total of 1788 patients underwent laparoscopic Roux-en-Y gastric bypass or laparoscopic sleeve gastrectomy between November 2007 and April 2015. The average follow-up consisted of 33.5 months, without loss to follow-up. Abdominal pain was presented in 387 patients (21.6%). The study population consisted of 337 women (87.1%) and 50 men (12.9%); the mean age was 43.3 years (standard deviation 10.1) and the median preoperative body mass index was 43.7 kg/m². An explanation for abdominal pain was found in 246 of 387 patients (63.6%), whereas no explanation was found in 133 patients (34.4%). Revisional surgery was a significant predictor for unexplained pain (odds ratio 1.7; confidence interval 1.0-2.8; P = 0.037).

CONCLUSION

A total of 133 patients (7.4%) experienced unexplained abdominal pain after laparoscopic bariatric surgery. Revisional surgery was found to be a significant predictive factor for this outcome. Present study results suggest that postoperative unexplained abdominal pain is a significant morbidity and should be part of the informed consent. More research is needed regarding further diagnosis and management and treatment.

摘要

背景

减重手术后的总体并发症发生率为 6.3%-10%。排除解剖/物理原因后,仍有相当一部分患者出现不明原因的术后腹痛。

目的

调查腹腔镜 Roux-en-Y 胃旁路术或腹腔镜袖状胃切除术患者术后出现不明原因腹痛的发生率,并确定其发生的预测因素。

地点

荷兰阿姆斯特丹肥胖症中心。

方法

对前瞻性数据库中的回顾性研究进行了评估。对基线特征和术后过程进行了评估。

结果

2007 年 11 月至 2015 年 4 月期间,共有 1788 例患者接受了腹腔镜 Roux-en-Y 胃旁路术或腹腔镜袖状胃切除术。平均随访时间为 33.5 个月,无失访。387 例(21.6%)患者出现腹痛。研究人群中 337 例为女性(87.1%),50 例为男性(12.9%);平均年龄为 43.3 岁(标准差 10.1),术前平均体重指数为 43.7kg/m²。在 387 例腹痛患者中,246 例(63.6%)有腹痛原因,133 例(34.4%)无明确病因。翻修手术是不明原因腹痛的显著预测因素(比值比 1.7;95%置信区间 1.0-2.8;P = 0.037)。

结论

腹腔镜减重手术后共有 133 例(7.4%)患者出现不明原因腹痛。翻修手术是该结局的显著预测因素。本研究结果表明,术后不明原因腹痛是一种严重的发病率,应纳入知情同意范围。还需要更多的研究来确定进一步的诊断、管理和治疗方法。

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