深入了解多形性日光疹中的免疫细胞浸润。
Insight into immunocytes infiltrations in polymorphous light eruption.
机构信息
Department of Dermatology, First Affiliated Hospital of Kunming Medical University, Institute of Dermatology & Venereology of Yunnan Province, Kunming, Yunnan, China.
Department of Physiology, School of Basic Medical Sciences, Kunming Medical University, Kunming, Yunnan, China.
出版信息
Biotechnol Adv. 2017 Nov 1;35(6):751-757. doi: 10.1016/j.biotechadv.2017.07.006. Epub 2017 Jul 17.
Polymorphous light eruption (PLE) which is one of the most common photodermatoses has been demonstrated to be immune-mediated disorder. Resistance to UV-induced immunosuppression resulting from differential immune cells infiltration and cytokines secretion has been highlighted in the pathogenesis of PLE. In this study, we reviewed differential patterns of immune cells infiltrations and cytokines secretion that may contribute to PLE occurrence and development.
多形性日光疹（PLE）是最常见的光皮病之一，现已证实其为免疫介导的疾病。PLE 的发病机制中突出了对 UV 诱导免疫抑制的抵抗，这是由于免疫细胞浸润和细胞因子分泌的差异所致。在本研究中，我们综述了可能导致 PLE 发生和发展的免疫细胞浸润和细胞因子分泌的差异模式。
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