Gastpar H, Sauer P H
Dtsch Med Wochenschr. 1986 Jun 27;111(26):1022-4. doi: 10.1055/s-2008-1068576.
Intranasal provocation tests followed by rhinomanometry were performed on 49 males with defined pollen allergy. Subsequently each patient took two tablets of tritoqualine, 100 mg each, three times daily for four or five days. Intranasal provocation was then repeated with the same allergen and flow again measured by rhinomanometry. There was a highly significant, treatment-induced rise in breath-flow through both nasal passages. The drug was well tolerated and no side effects, in particular no sedative action, were observed.
对49名确诊花粉过敏的男性进行了鼻内激发试验，随后进行鼻阻力测量。随后，每位患者每天服用两片曲喹那敏，每片100毫克，每天三次，持续四或五天。然后用相同的过敏原再次进行鼻内激发试验，并再次通过鼻阻力测量来测定气流。治疗后，通过两个鼻腔通道的气流有极显著的增加。该药物耐受性良好，未观察到副作用，尤其是没有镇静作用。
