Bulloch Andrew G M, Williams Jeanne V A, Lavorato Dina H, Patten Scott B
Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada; Department of Psychiatry, University of Calgary, Calgary, Alberta, Canada; Mathison Centre for Mental Health Research & Education, Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada.
Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.
J Affect Disord. 2017 Dec 1;223:65-68. doi: 10.1016/j.jad.2017.06.007. Epub 2017 Jul 4.
Marital status is associated with major depression prevalence, however, the strength of association may be modified by age and gender.
The data sources were a series of cross sectional national health surveys of the Canadian population carried out by Statistics Canada during 1996-2013. These were cross-sectional files from the National Population Health Survey of 1996, together with the Canadian Community Health Surveys from 2000 to 2013; the respondents were 18 years and older. The data was analyzed with meta-analytic techniques and logistic regression.
In terms of gender, the odds ratios of depression were smaller for females (vs males) who were single, widowed or separated compared to married people. Regarding age, the odds ratios for depression showed a steady rise with increasing age for those in single and in common-law relationships compared to married people. In contrast the odds ratios for depression declined with age for those widowed, separated and divorced compared to married people. The strength of the interaction terms used to quantify these moderating effects showed no change from 1996 to 2013.
Only one member of each household was included, so that relationship issues could not be studied. The generalizability of our findings requires international data. Also the diagnostic interviews used are not as accurate as clinical assessments.
Use of large numbers of participants has revealed some robust modifying effects of both gender and age on the depression/marital status relationship. The clinical significance of our findings is that the vulnerability to development of depression is not only related to marital status, but that this relationship is modified by age and gender.
婚姻状况与重度抑郁症患病率相关,然而,这种关联的强度可能会因年龄和性别而改变。
数据来源是加拿大统计局在1996 - 2013年期间对加拿大人口进行的一系列横断面全国健康调查。这些数据包括1996年全国人口健康调查的横断面文件以及2000年至2013年的加拿大社区健康调查;受访者年龄在18岁及以上。采用荟萃分析技术和逻辑回归对数据进行分析。
在性别方面,与已婚者相比,单身、丧偶或分居的女性(与男性相比)患抑郁症的比值比更小。在年龄方面,与已婚者相比,单身和同居关系者患抑郁症的比值比随着年龄增长呈稳步上升。相比之下,与已婚者相比,丧偶、分居和离婚者患抑郁症的比值比随年龄下降。用于量化这些调节效应的交互项强度在1996年至2013年期间没有变化。
每户仅纳入一名成员,因此无法研究关系问题。我们研究结果的普遍性需要国际数据支持。此外,所使用的诊断访谈不如临床评估准确。
大量参与者的研究揭示了性别和年龄对抑郁症/婚姻状况关系产生的一些显著调节效应。我们研究结果的临床意义在于,患抑郁症的易感性不仅与婚姻状况有关,而且这种关系会因年龄和性别而改变。