Sharma Ghimire Prakriti, Jin Cheng
State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, China.
University of Chinese Academy of Sciences, Beijing, 100101, China.
Curr Microbiol. 2017 Oct;74(10):1226-1236. doi: 10.1007/s00284-017-1308-9. Epub 2017 Jul 22.
Filamentous fungi play a dynamic role in health and the environment. In addition, their unique and complex hyphal structures are involved in their morphogenesis, integrity, synthesis, and degradation, according to environmental and physiological conditions and resource availability. However, in biotechnology, it has a great value in the production of enzymes, pharmaceuticals, and food ingredients. The beginning of nomenclature of overall fungi started in early 1990 after which the categorization, interior and exterior mechanism, function, molecular and genetics study took pace. This mini-review has emphasized some of the important aspects of filamentous fungi, their pattern of life cycle, history, and development of different strategic methods applied to exploit this unique organism. New trends and concepts that have been applied to overcome obstacle because of their basic structure related to genomics and systems biology has been presented. Furthermore, the future aspects and challenges that need to be deciphered to get a bigger and better picture of filamentous fungi have been discussed.
丝状真菌在健康和环境方面发挥着重要作用。此外，根据环境、生理条件和资源可用性，其独特而复杂的菌丝结构参与了形态发生、完整性、合成和降解过程。然而，在生物技术领域，丝状真菌在酶、药物和食品成分的生产中具有巨大价值。整个真菌命名法始于20世纪90年代初，此后分类、内外机制、功能、分子和遗传学研究迅速展开。本综述强调了丝状真菌的一些重要方面、其生命周期模式、历史以及为利用这种独特生物体而应用的不同战略方法的发展。还介绍了由于其与基因组学和系统生物学相关的基本结构而应用于克服障碍的新趋势和概念。此外，还讨论了为更全面、更深入地了解丝状真菌而需要破解的未来方向和挑战。
