Samura Takaaki, Toda Koichi, Yoshioka Daisuke, Nakamura Teruya, Miyagawa Shigeru, Yoshikawa Yasushi, Saito Shunsuke, Domae Keitaro, Sawa Yoshiki
Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
Ann Thorac Surg. 2017 Aug;104(2):e109-e111. doi: 10.1016/j.athoracsur.2017.01.073.
Libman-Sacks endocarditis is a cardiac manifestation of systemic lupus erythematosus (SLE) and antiphospholipid syndrome. We report a case of mitral valve destruction due to Libman-Sacks endocarditis, which was caused by activation of SLE, despite prompt initiation of systemic steroid therapy. The prevention of SLE activation is critically important in valve surgery for patients with SLE. To the best of our knowledge, this is the first case of repaired mitral valve destruction due to activation of SLE, which was caused by valve surgery itself.
利布曼-萨克斯心内膜炎是系统性红斑狼疮（SLE）和抗磷脂综合征的心脏表现。我们报告一例因利布曼-萨克斯心内膜炎导致二尖瓣破坏的病例，尽管及时开始了全身类固醇治疗，但仍由SLE激活所致。对于SLE患者，预防SLE激活在瓣膜手术中至关重要。据我们所知，这是首例因瓣膜手术本身导致SLE激活而引起二尖瓣修复后破坏的病例。
