Weatherhead Jill E, Hotez Peter J, Mejia Rojelio
Department of Pediatrics, Section of Tropical Medicine, Baylor College of Medicine, Feigin Research Building, 1102 Bates Avenue, Suite 550, Houston, TX 77030, USA; National School of Tropical Medicine, Baylor College of Medicine, One Baylor Plaza, MS: BCM-113, Houston, TX 77030, USA.
Department of Pediatrics, Section of Tropical Medicine, Baylor College of Medicine, Feigin Research Building, 1102 Bates Avenue, Suite 550, Houston, TX 77030, USA; National School of Tropical Medicine, Baylor College of Medicine, One Baylor Plaza, MS: BCM-113, Houston, TX 77030, USA; Department of Molecular Virology and Microbiology, Baylor College of Medicine, One Baylor Plaza, MS: BCM-385, Houston, TX 77030, USA; Sabin Vaccine Institute and Texas Children's Hospital (TCH), Center for Vaccine Development, Feigin Research Building, 1102 Bates Avenue, Suite 550, Houston, TX 77030, USA.
Pediatr Clin North Am. 2017 Aug;64(4):867-877. doi: 10.1016/j.pcl.2017.03.005.
Helminth infections, including soil-transmitted helminths and schistosomiasis, remain one of the most common infections in the world with over 1 billion people infected. These infections cause significant morbidity, particularly in young children, that may last a lifetime, including growth and cognitive stunting. There is an urgent need for the control and elimination of helminth infections from areas of poverty to reduce morbidity in children. Mass drug administration programs were adopted by the World Health Assembly in 2001 and have evolved to provide coverage with multiple anthelmintic medications in a single rapid impact package and more extensive coverage within a community.
蠕虫感染,包括土源性蠕虫感染和血吸虫病,仍然是世界上最常见的感染之一,感染人数超过10亿。这些感染会导致严重的发病情况,尤其是在幼儿中,可能会持续一生,包括生长发育迟缓和认知发育迟缓。迫切需要在贫困地区控制和消除蠕虫感染,以降低儿童的发病率。世界卫生大会于2001年通过了大规模药物驱虫计划,该计划已发展为在一个单一的快速影响方案中提供多种驱虫药物的覆盖范围,并在社区内实现更广泛的覆盖。