Badri Milad, Olfatifar Meysam, Gharibi Zahra, Pal Mahendra, Hatam-Nahavandi Kareem, Asghari Ali, Sgroi Giovanni, Soltani Hanieh, Abdoli Amir, Eslahi Aida Vafae
Medical Microbiology Research Center, Qazvin University of Medical Sciences, Qazvin, Iran.
Gastroenterology and Hepatology Diseases Research Center, Qom University of Medical Sciences, Qom, Iran.
BMC Public Health. 2025 Aug 19;25(1):2852. doi: 10.1186/s12889-025-23958-9.
Neglected tropical diseases (NTDs) are responsible for substantial illness and death worldwide. Helminthic infections among school-aged children pose a serious public health challenge due to their detrimental effects on health and development.
A wide-ranging search conducted across five databases, including Scopus, EMBASE, PubMed, Web of Science, and Google Scholar to retrieve papers published between 1998 and 2024. To evaluate the combined prevalence, a random-effects model with a 95% confidence interval (CI) was applied, and the statistical analysis was performed using meta-analysis packages in R version (3.6.1).
There were 190 eligible studies documented in 42 countries, and 199,988 schoolchildren included in this review. The global prevalence of helminthic parasites was 20.6% (17.2- 24.3%). Among the countries studied, Tanzania and Vietnam showed the highest levels of prevalence at 67.41% and 65.04%, respectively, with Toxocara spp. and Ascaris lumbricoides being the most prevalent helminthic parasites at 10.36% and 9.47%, respectively.
In conclusion, this study underscores the pressing public health concern of helminthic infections among schoolchildren, largely driven by inadequate sanitation and poor water quality. Prompt action, such as improving sanitation, expanding school-based deworming programs, and enhancing access to safe water, is crucial to control these infections and enhance overall health outcomes.
被忽视的热带病在全球范围内导致大量疾病和死亡。学龄儿童的蠕虫感染因其对健康和发育的有害影响而构成严重的公共卫生挑战。
在包括Scopus、EMBASE、PubMed、Web of Science和谷歌学术在内的五个数据库中进行广泛检索，以获取1998年至2024年发表的论文。为评估合并患病率，应用了具有95%置信区间（CI）的随机效应模型，并使用R版本（3.6.1）中的荟萃分析软件包进行统计分析。
42个国家记录了190项符合条件的研究，本综述纳入了199,988名学童。蠕虫寄生虫的全球患病率为20.6%（17.2 - 24.3%）。在所研究的国家中，坦桑尼亚和越南的患病率最高，分别为67.41%和65.04%，其中弓蛔虫属和蛔虫是最常见的蠕虫寄生虫，分别为10.36%和9.47%。
总之，本研究强调了学龄儿童蠕虫感染这一紧迫的公共卫生问题，这在很大程度上是由卫生设施不足和水质差所驱动的。迅速采取行动，如改善卫生条件、扩大学校驱虫计划以及增加安全饮用水的供应，对于控制这些感染和改善整体健康状况至关重要。
