Fleet Julie-Anne, Jones Meril, Belan Ingrid
School of Nursing&Midwifery, The University of South Australia, GPO Box 2471, Adelaide, South Australia 5001, Australia.
School of Nursing&Midwifery, Flinders University, GPO Box 2100, Adelaide, South Australia 5001, Australia.
Midwifery. 2017 Oct;53:15-19. doi: 10.1016/j.midw.2017.07.006. Epub 2017 Jul 8.
To compare women's experience of receiving either intranasal fentanyl, subcutaneous fentanyl or intramuscular pethidine for labour analgesia.
A content analysis was undertaken as part of the third phase of a larger randomised controlled trial, using the per-protocol dataset to examine women's experiences of treatment received. Healthy women birthing at term, who received intranasal fentanyl (n=41), subcutaneous fentanyl (n=37) and/or intramuscular pethidine (n=38) for labour analgesia, were contacted at 6 weeks postpartum to complete a phone questionnaire.
A tertiary and regional maternity unit in South Australia.
Over 80% of women who received intranasal or subcutaneous fentanyl reported that they would use the treatment again compared to 44.8% of women who had received pethidine (self-administered intranasal fentanyl provided more expressive responses emphasising the route provided a strong sense of control and enablement.
Route of administration influenced the women's experience, more women who self-administered intranasal fentanyl reported positive emotional responses, with women reporting increased autonomy and satisfaction. Whereas, women who relied on the midwife to administer subcutaneous fentanyl or intramuscular pethidine, were more often focused on the physical effect of the drug. Pethidine was the least preferred option due to adverse effects.
For women requesting parenteral analgesia, fentanyl administered by less invasive routes offers women additional options that may better meet their emotional, cognitive and physical needs than the current practice of administering intramuscular pethidine.
比较女性接受鼻内芬太尼、皮下芬太尼或肌肉注射哌替啶进行分娩镇痛的体验。
作为一项更大规模随机对照试验第三阶段的一部分,进行了内容分析,使用符合方案数据集来检查女性接受治疗的体验。在产后6周联系足月分娩的健康女性,她们接受了鼻内芬太尼(n = 41)、皮下芬太尼(n = 37)和/或肌肉注射哌替啶(n = 38)进行分娩镇痛,以完成电话问卷调查。
南澳大利亚的一家三级区域产科单位。
超过80%接受鼻内或皮下芬太尼的女性表示她们会再次使用该治疗,而接受哌替啶的女性这一比例为44.8%(自行给药的鼻内芬太尼提供了更丰富的反馈,强调该给药途径带来了强烈的控制感和自主感)。
给药途径影响了女性的体验,更多自行给药鼻内芬太尼的女性报告了积极的情绪反应,女性报告自主性和满意度增加。而依赖助产士给予皮下芬太尼或肌肉注射哌替啶的女性,更多关注药物的身体效果。由于不良反应,哌替啶是最不受欢迎的选择。
对于要求非肠道镇痛的女性,通过侵入性较小的途径给予芬太尼为女性提供了额外的选择,可能比目前肌肉注射哌替啶的做法更好地满足她们的情感、认知和身体需求。