Arosemena Coronel M, Sánchez Armijos J, Tettamanti Miranda D, Vásquez Cedeño D, Mariani Carrera R, Navarro Chávez M, Castillo P R
Department of Medicine, Luis Vernaza Hospital, Ecuador.
Department of Medicine, Universidad Católica Santiago de Guayaquil, Ecuador.
Sleep Med. 2017 Aug;36:6-9. doi: 10.1016/j.sleep.2017.04.012. Epub 2017 May 15.
This study aimed to determine the frequency of sleep disorders in hypoglycemic diabetic patients and possible relationships with scores of sleep disorders and restless legs syndrome in mestizo population in Guayaquil, Ecuador.
A multicenter, cross-sectional study conducted at an outpatient endocrinology clinic in urban and rural Ecuador regions, included 290 participants with type 2 diabetes mellitus with severe hypoglycemic episodes, completed, validated, and culturally adapted sleep questionnaires to assess daytime sleepiness, risk of sleep apnea and restless legs syndrome. Logistic regression analysis was conducted to identify factors associated with severe hypoglycemia.
The prevalence of EDS was 56.8%, RLS prevalence of 46.2%, and 38.6% prevalence of high risk Berlin score. Multivariate logistic regression indicated hypoglycemic T2DM in the range of 56-75 years old were more likely to have high ESS (p 0.0001).
A high prevalence of sleep disorders in diabetic Latinos living in Ecuador was evidenced. The presence of somnolence in patients older than 56 years and high HbA1c levels should alert the clinician for the occurrence of hypoglycemic episodes.
本研究旨在确定厄瓜多尔瓜亚基尔混血人群中低血糖糖尿病患者睡眠障碍的发生率，以及睡眠障碍评分与不安腿综合征之间的可能关系。
在厄瓜多尔城乡地区的一家门诊内分泌诊所进行的一项多中心横断面研究，纳入了290名患有严重低血糖发作的2型糖尿病患者，完成、验证并进行文化适应性调整的睡眠问卷，以评估白天嗜睡、睡眠呼吸暂停风险和不安腿综合征。进行逻辑回归分析以确定与严重低血糖相关的因素。
EDS的患病率为56.8%，RLS患病率为46.2%，高风险柏林评分患病率为38.6%。多变量逻辑回归表明，56至75岁范围内的低血糖2型糖尿病患者更有可能有高ESS（p = 0.0001）。
居住在厄瓜多尔的糖尿病拉丁裔人群中睡眠障碍的高患病率得到了证实。56岁以上患者出现嗜睡和高HbA1c水平应提醒临床医生注意低血糖发作的发生。
