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流动供体面临的挑战:加拿大肾脏配对交换项目中供体检查与供体手术之间的差异

Challenges for the Travelling Donor: Variability Between Donor Workup and Donor Surgery in the Canadian Kidney Paired Exchange Program.

作者信息

Reikie B A, Kroczak T, McGregor T B

机构信息

Department of Surgery, University of Manitoba, Winnipeg, Canada.

Department of Surgery, University of Toronto, Toronto, Canada.

出版信息

Transplant Proc. 2017 Jul-Aug;49(6):1232-1236. doi: 10.1016/j.transproceed.2017.01.082.

DOI:10.1016/j.transproceed.2017.01.082
PMID:28735986
Abstract

BACKGROUND

A primary obstacle to providing renal transplantation is limited access to donated kidneys. The living-donor pool for renal allografts was greatly expanded through implementation of a kidney paired donation program. Whereas some programs ship donor kidneys to the site of renal transplantation, others send the donor to the site of transplantation. Performing the nephrectomy and transplantation at the same location may optimize functional renal outcomes, but preferred surgical approaches may differ between surgical teams performing the donor workup and donor surgery. Our objective was to identify incongruence between the surgery planned by the team that performed the donor's workup, and the surgery that took place at the site of donation.

METHODS

A retrospective chart review was performed between the site of preoperative surgical planning, and the site of surgery for kidney donors in the Canadian kidney paired donation program.

RESULTS

Fifty-one donors were preoperatively prepared in any of six Canadian provinces, and then underwent surgery in a different province. The surgical procedure performed for 31% of the patients' nephrectomies differed from the procedure suggested by the surgical team who conducted the preoperative workup. Half of these differences were between left laparoscopic and left laparoscopic hand-assisted, but the remainder included more substantial changes of sides and/or laparoscopic versus open procedures.

CONCLUSION

Optimal patient care is challenged in a kidney paired donation program that uses the "traveling donor" approach due to differing surgical techniques selected by the surgeon at the site of donor workup and the surgeon at the site of donation.

摘要

背景

肾移植面临的一个主要障碍是可获得的捐赠肾脏数量有限。通过实施肾脏配对捐赠计划,肾移植活体供体库得到了极大扩充。有些计划将供体肾脏运往肾移植地点,而有些则将供体送往移植地点。在同一地点进行肾切除术和移植术可能会优化肾脏功能结局,但在进行供体评估和供体手术的手术团队之间,首选的手术方法可能有所不同。我们的目标是确定进行供体评估的团队所计划的手术与捐赠地点实际进行的手术之间是否存在不一致。

方法

对加拿大肾脏配对捐赠计划中肾脏供体的术前手术规划地点和手术地点进行了回顾性图表审查。

结果

51名供体在加拿大的六个省份中的任何一个进行了术前准备,然后在另一个省份接受手术。31%的患者肾切除术所采用的手术方式与进行术前评估的手术团队建议的方式不同。其中一半的差异存在于左侧腹腔镜手术和左侧腹腔镜辅助手术之间,但其余差异包括手术部位和/或腹腔镜手术与开放手术之间更显著的变化。

结论

在采用“流动供体”方法的肾脏配对捐赠计划中,由于供体评估地点的外科医生和捐赠地点的外科医生选择的手术技术不同,最佳患者护理受到挑战。

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Challenges for the Travelling Donor: Variability Between Donor Workup and Donor Surgery in the Canadian Kidney Paired Exchange Program.流动供体面临的挑战:加拿大肾脏配对交换项目中供体检查与供体手术之间的差异
Transplant Proc. 2017 Jul-Aug;49(6):1232-1236. doi: 10.1016/j.transproceed.2017.01.082.
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引用本文的文献

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Financial Costs Incurred by Living Kidney Donors: A Prospective Cohort Study.活体肾捐献者的经济成本:一项前瞻性队列研究。
J Am Soc Nephrol. 2018 Dec;29(12):2847-2857. doi: 10.1681/ASN.2018040398. Epub 2018 Nov 7.
2
Kidney exchange transplantation current status, an update and future perspectives.肾交换移植的现状、最新进展及未来展望。
World J Transplant. 2018 Jun 28;8(3):52-60. doi: 10.5500/wjt.v8.i3.52.
3
Kidney paired donation and the unique challenges of kidney shipment in Canada.加拿大的肾脏配对捐赠及肾脏运输的独特挑战。
Can J Surg. 2018 Apr;61(2):139-140. doi: 10.1503/cjs.008017.