Department of Medicine and Department of Clinical Epidemiology and Biostatistics, London Health Sciences Centre, Western University, London, Ontario, Canada.
Division of Nephrology, Dalhousie University, Halifax, Nova Scotia, Canada.
J Am Soc Nephrol. 2018 Dec;29(12):2847-2857. doi: 10.1681/ASN.2018040398. Epub 2018 Nov 7.
Approximately 40% of the kidneys for transplant worldwide come from living donors. Despite advantages of living donor transplants, rates have stagnated in recent years. One possible barrier may be costs related to the transplant process that potential willing donors may incur for travel, parking, accommodation, and lost productivity.
To better understand and quantify the financial costs incurred by living kidney donors, we conducted a prospective cohort study, recruiting 912 living kidney donors from 12 transplant centers across Canada between 2009 and 2014; 821 of them completed all or a portion of the costing survey. We report microcosted total, out-of-pocket, and lost productivity costs (in 2016 Canadian dollars) for living kidney donors from donor evaluation start to 3 months after donation. We examined costs according to () the donor's relationship with their recipient, including spousal (donation to a partner), emotionally related nonspousal (friend, step-parent, in law), or genetically related; and () donation type (directed, paired kidney, or nondirected).
Living kidney donors incurred a median (75th percentile) of $1254 ($2589) in out-of-pocket costs and $0 ($1908) in lost productivity costs. On average, total costs were $2226 higher in spousal compared with emotionally related nonspousal donors (=0.02) and $1664 higher in directed donors compared with nondirected donors (<0.001). Total costs (out-of-pocket and lost productivity) exceeded $5500 for 205 (25%) donors.
Our results can be used to inform strategies to minimize the financial burden of living donation, which may help improve the donation experience and increase the number of living donor kidney transplants.
全球大约有 40%的移植用肾脏来自活体供者。尽管活体供者移植具有优势,但近年来其比例已停滞不前。潜在的愿意捐献者可能会因为旅行、停车、住宿和生产力损失而产生与移植过程相关的费用,这可能是一个障碍。
为了更好地了解和量化活体肾脏供者所产生的财务成本,我们进行了一项前瞻性队列研究,于 2009 年至 2014 年间从加拿大 12 个移植中心招募了 912 名活体肾脏供者;其中 821 名供者完成了全部或部分成本调查。我们报告了从供者评估开始到捐献后 3 个月期间,每位活体肾脏供者的微成本总费用、自付费用和生产力损失(以 2016 年加拿大元计)。我们根据供者与受者的关系(包括配偶[捐赠给伴侣]、情感相关的非配偶[朋友、继父母、姻亲]或遗传相关])和捐赠类型(定向、配对肾脏或非定向)来检查成本。
活体肾脏供者的自付费用中位数(75 百分位数)为 1254 美元(2589 美元),生产力损失费用中位数为 0 美元(1908 美元)。平均而言,配偶供者的总费用比情感相关的非配偶供者高 2226 美元(=0.02),定向供者的总费用比非定向供者高 1664 美元(<0.001)。205 名(25%)供者的总费用(自付费用和生产力损失)超过 5500 美元。
我们的研究结果可用于制定策略,以减轻活体捐献的经济负担,这可能有助于改善捐献体验并增加活体供者肾脏移植的数量。