Zeng Fanchang, Lian Xin, Zhang Guirong, Yu Xiaoman, Bradley Carl A, Ming Ray
State Key Laboratory of Crop Biology, College of Agronomy, Shandong Agricultural University, Tai'an, Shandong 271018, China.
Department of Plant Biology, University of Illinois, Urbana, IL 61801, USA.
Genom Data. 2017 Jul 8;13:54-63. doi: 10.1016/j.gdata.2017.07.007. eCollection 2017 Sep.
Fungi are the causal agents of many of the world's most serious plant diseases causing disastrous consequences for large-scale agricultural production. Pathogenicity genomic basis is complex in fungi as multicellular eukaryotic pathogens. Here, we report the genome sequence of , and comparative genome analysis with plant pathogen members of the genus ( (synonyms ), , and - pathogens of wheat, pine, poplar and banana, respectively). Synteny or collinearity was limited between genomes of major pathogens. Comparative analysis with these related pathogen genomes indicated distinct genome-wide repeat organization features. It suggests repetitive elements might be responsible for considerable evolutionary genomic changes. These results reveal the background of genomic differences and similarities between species. Wide diversity as well as conservation on genome features forms the potential genomic basis of the pathogen specialization, such as pathogenicity to woody vs. herbaceous hosts. Through comparative genome analysis among five species, our results have shed light on the genome features of these related fungi species. It provides insight for understanding the genomic basis of fungal pathogenicity and disease resistance in the crop hosts.
真菌是世界上许多最严重植物病害的病原体，给大规模农业生产带来灾难性后果。作为多细胞真核病原体，真菌的致病性基因组基础很复杂。在此，我们报告了[具体物种]的基因组序列，并与[属名]的植物病原体成员（分别是小麦、松树、杨树和香蕉的病原体[具体学名]（同义词[其他学名]）、[其他学名]、[其他学名]和[其他学名]）进行了比较基因组分析。主要[属名]病原体的基因组之间共线性或同源性有限。与这些相关病原体基因组的比较分析表明了全基因组重复序列组织特征的差异。这表明重复元件可能是基因组发生大量进化变化的原因。这些结果揭示了[属名]物种之间基因组差异和相似性的背景。基因组特征的广泛多样性以及保守性构成了病原体专业化的潜在基因组基础，例如对木本宿主与草本宿主的致病性。通过对五个[属名]物种进行比较基因组分析，我们的结果揭示了这些相关真菌物种的基因组特征。这为理解真菌致病性和作物宿主抗病性的基因组基础提供了见解。
