Noel Cory
Coronary Anomalies Program, Division of Pediatric Cardiology, Texas Children's Hospital, Houston, Texas, USA.
Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA.
Congenit Heart Dis. 2017 Sep;12(5):627-629. doi: 10.1111/chd.12501. Epub 2017 Jul 24.
Myocardial ischemia is an insult that is primarily thought of in an adult population. However, there are several congenital and acquired cardiac lesions that may lead to myocardial ischemia in a pediatric population. One of the prominent congenital lesions is anomalous aortic origin of a coronary artery (AAOCA). Anomalous aortic origin of a coronary artery is one of the leading causes sudden cardiac death in pediatric and young adult patients, and thus the assessment of myocardial perfusion is of the utmost importance. Over the past decade, pharmacologic stress MRI has proven to be a highly sensitive and accurate diagnostic examination for qualifying myocardial perfusion in adults with coronary artery disease. This noninvasive imaging modality may be a useful tool in assessing the function impact of AAOCA on myocardial perfusion.
心肌缺血主要被认为是成年人群中出现的一种损伤。然而，有几种先天性和后天性心脏病变可能导致儿科人群出现心肌缺血。其中一种突出的先天性病变是冠状动脉异常起源于主动脉（AAOCA）。冠状动脉异常起源于主动脉是儿科和年轻成年患者心脏性猝死的主要原因之一，因此对心肌灌注的评估至关重要。在过去十年中，药物负荷磁共振成像已被证明是诊断成年冠心病患者心肌灌注的一种高度敏感且准确的检查方法。这种非侵入性成像方式可能是评估AAOCA对心肌灌注功能影响的有用工具。
