Johnson C S, Rosen P J, Sheehan W W
Am J Clin Pathol. 1979 Jul;72(1):118-21. doi: 10.1093/ajcp/72.1.118.
Pathologic rupture of the spleen is a rare phenomenon in acute lymphocytic leukemia, and its mechanism is unknown. This complication has been seen almost exclusively in men, and at ages much older than those of the majority of patients who have this leukemia; these unusual features are also unexplained. A case of acute lymphoctyic leukemia with pathologic rupture of the spleen in which the pathologic findings suggest that the splenic rupture was due to infiltration and destruction of the splenic capsule by leukemic cells is reported.
脾脏病理性破裂在急性淋巴细胞白血病中是一种罕见现象，其机制尚不清楚。这种并发症几乎仅见于男性，且发病年龄比大多数患此白血病的患者大得多；这些不寻常的特征也无法解释。本文报告一例急性淋巴细胞白血病合并脾脏病理性破裂的病例，病理检查结果提示脾脏破裂是由于白血病细胞浸润和破坏脾包膜所致。
