Altès A, Brunet S, Martinez C, Soler J, Ayats R, Sureda A, López R, Domingo A
Department d'Hematologia, Hospital de Sant Pau, Barcelona, Spain.
Ann Hematol. 1994 Mar;68(3):143-4. doi: 10.1007/BF01727419.
Spontaneous splenic rupture is a rare, though life-threatening complication of some hematological malignancies and is even more infrequent as the initial symptom of acute lymphoblastic leukemia. We describe the fourth case, to our knowledge, of acute lymphoblastic leukemia presenting as splenic rupture, and for the first time the immunophenotype and cytogenetic pattern observed.
自发性脾破裂是某些血液系统恶性肿瘤罕见但危及生命的并发症，作为急性淋巴细胞白血病的首发症状则更为罕见。据我们所知，我们描述了第四例以脾破裂为表现的急性淋巴细胞白血病病例，并首次观察到其免疫表型和细胞遗传学模式。
