分娩前、分娩期间及分娩后胃动素、生长抑素和胰多肽的血浆浓度。

Plasma concentrations of motilin, somatostatin and pancreatic polypeptide before, during and after parturition.

作者信息

Jenssen T G, Holst N, Burhol P G, Jorde R, Maltau J M, Vonen B

出版信息

Acta Obstet Gynecol Scand. 1986;65(2):153-6. doi: 10.3109/00016348609158371.

Abstract

The plasma concentrations of the gastrointestinal regulatory peptides motilin, somatostatin and pancreatic polypeptide were measured in 6 pregnant women, 17-35 years old. Plasma samples were drawn 2-3 weeks before, during, and immediately after labor, and 24 h as well as 1 year after delivery. Plasma motilin levels did not change during labor, but peaked non-significantly upon delivery, and were thereafter significantly elevated 24 h post partum (p less than 0.05). Plasma motilin concentrations measured one year after delivery were almost identical with the pre-term values. Plasma somatostatin rose non-significantly during labor and peaked transiently upon delivery (p less than 0.05), whereas plasma pancreatic polypeptide increased significantly during the second stage of labor (p less than 0.05). The plasma motilin increase may be part of a compensatory mechanism leading to augmented gastrointestinal motility after delivery.

摘要

对6名年龄在17至35岁之间的孕妇测定了胃肠调节肽胃动素、生长抑素和胰多肽的血浆浓度。在分娩前2至3周、分娩期间、分娩后即刻、产后24小时以及产后1年采集血样。血浆胃动素水平在分娩期间没有变化，但在分娩时非显著性达到峰值，此后在产后24小时显著升高（p<0.05）。分娩1年后测得的血浆胃动素浓度与早产时的值几乎相同。血浆生长抑素在分娩期间非显著性升高，并在分娩时短暂达到峰值（p<0.05），而血浆胰多肽在分娩第二阶段显著增加（p<0.05）。血浆胃动素的增加可能是导致产后胃肠动力增强的一种代偿机制的一部分。