Holst N, Jenssen T G, Burhol P G, Jorde R, Maltau J M, Haug E
Br J Obstet Gynaecol. 1986 Feb;93(2):188-93. doi: 10.1111/j.1471-0528.1986.tb07885.x.
The circulating levels of prolactin (PRL), vasoactive intestinal polypeptide (VIP), somatostatin (SRIH), cholecystokinin (CCK), pancreatic polypeptide (PP), insulin, motilin and blood glucose were measured in nine nursing women 27-40 days after delivery to establish the possible role of some gastrointestinal regulatory peptides in human breast feeding. During the last 20 min of suckling a significant (P less than 0.05) increase in serum PRL was observed concomitantly with a significant decrease in plasma SRIH levels (P less than 0.05 at 20 min and P less than 0.01 at 30 min). There was a highly significant inverse correlation between mean PRL and SRIH levels during the first 30 min of breast feeding (r = -0.996, P less than 0.001). Pancreatic polypeptide (pp) also increased significantly (P less than 0.01) during nursing, while there were no changes in the plasma levels of the other gastrointestinal regulatory peptides studied.
对9名产后27至40天的哺乳期妇女，检测了催乳素（PRL）、血管活性肠肽（VIP）、生长抑素（SRIH）、胆囊收缩素（CCK）、胰多肽（PP）、胰岛素、胃动素及血糖的循环水平，以确定某些胃肠调节肽在人类母乳喂养中的可能作用。在哺乳的最后20分钟内，观察到血清PRL显著升高（P<0.05），同时血浆SRIH水平显著降低（20分钟时P<0.05，30分钟时P<0.01）。母乳喂养开始后30分钟内，PRL与SRIH的平均水平呈高度显著负相关（r = -0.996，P<0.001）。哺乳期间胰多肽（PP）也显著升高（P<0.01），而所研究的其他胃肠调节肽的血浆水平无变化。
