过期妊娠中静脉滴注缩宫素期间的胃肠调节肽

Gastrointestinal regulatory peptides during oxytocin infusion in post-term pregnancies.

作者信息

Holst N, Jenssen T G, Burhol P G, Jorde R

机构信息

Department of Obstetrics and Gynaecology, University of Tromsø Norway.

出版信息

Acta Physiol Scand. 1988 Jan;132(1):23-7. doi: 10.1111/j.1748-1716.1988.tb08293.x.

DOI:10.1111/j.1748-1716.1988.tb08293.x

PMID:2906209

Abstract

The plasma concentrations of the gastrointestinal regulatory peptides vasoactive intestinal polypeptide (VIP), insulin, secretin, somatostatin, motilin, pancreatic polypeptide (PP) and gastric inhibitory polypeptide (GIP), as well as blood glucose, were measured in eight healthy women before, during and after oxytocin infusion in post-term pregnancies. Plasma VIP increased significantly (P less than 0.01) during oxytocin infusion. Plasma secretin showed a significant (P less than 0.05) decrease during oxytocin infusion. Plasma somatostatin remained unchanged during oxytocin infusion, but thereafter a significant (P less than 0.05) increase occurred. Both plasma motilin and plasma PP showed a non-significant increase during oxytocin infusion with sustained levels thereafter. No changes were found for plasma insulin, GIP and blood glucose.

摘要

在8名足月妊娠的健康女性中，于催产素输注前、输注期间及输注后，测定了胃肠调节肽血管活性肠肽（VIP）、胰岛素、促胰液素、生长抑素、胃动素、胰多肽（PP）和胃抑制多肽（GIP）的血浆浓度，以及血糖水平。在催产素输注期间，血浆VIP显著升高（P<0.01）。在催产素输注期间，血浆促胰液素显著降低（P<0.05）。在催产素输注期间，血浆生长抑素保持不变，但之后显著升高（P<0.05）。在催产素输注期间，血浆胃动素和血浆PP均有非显著性升高，之后维持在该水平。血浆胰岛素、GIP和血糖未发现变化。