Department of Chemical Engineering, Massachusetts Institute of Technology , Cambridge, Massachusetts 02139, United States.
Anal Chem. 2017 Aug 15;89(16):8524-8530. doi: 10.1021/acs.analchem.7b02264. Epub 2017 Aug 3.
Data on the solubilities of gases in liquids are foundational for assessing a variety of multiphase separations and gas-liquid reactions. Taking advantage of the tube-in-tube reactor design built with semipermeable Teflon AF-2400 tubes, liquids can be rapidly saturated without direct contacting of gas and liquid. The gas solubility can be determined by performing steady-state flux balances of both the gas and liquid flowing into the reactor system. Using this type of reactor, a fully automated strategy has been developed for the rapid in situ measurement of gas solubilities in liquids. The developed strategy enables precise gas solubility measurements within 2-5 min compared with 4-5 h using conventional methods. This technique can be extended to the discrete multipoint steady-state and continuous ramped-multipoint data acquisition methods. The accuracy of this method has been validated against several gas-liquid systems, showing less than 2% deviation from known values. Finally, this strategy has been extended to measure the temperature dependence of gas solubilities in situ and to estimate the local enthalpy of dissolution across a defined temperature range.
气体在液体中溶解度的数据对于评估各种多相分离和气液反应至关重要。利用带有半透性聚四氟乙烯 AF-2400 管的管式反应器设计，可以在不直接接触气体和液体的情况下快速使液体饱和。通过对流入反应器系统的气体和液体进行稳态通量平衡，可以确定气体的溶解度。使用这种类型的反应器，已经开发出一种用于快速原位测量液体中气体溶解度的全自动策略。与传统方法相比，该策略可以在 2-5 分钟内实现精确的气体溶解度测量，而传统方法需要 4-5 小时。该技术可以扩展到离散多点稳态和连续斜坡多点数据采集方法。该方法的准确性已经通过几个气液系统得到验证，与已知值的偏差小于 2%。最后，该策略已扩展到原位测量气体溶解度随温度的变化，并估计在定义的温度范围内局部溶解焓。
