Zimmerman Mark, Gorlin Eugenia, Dalrymple Kristy, Chelminiski Iwona
Department of Psychiatry and Human Behavior, the Warren Alpert Medical School of Brown University, Providence, RI, USA, E-mail:
Ann Clin Psychiatry. 2017 Aug;29(3):160-166.
Attention-deficit/hyperactivity disorder (ADHD) is a serious illness that is frequently underdiagnosed in adults. The goal of this report from the Rhode Island Methods to Improve Diagnostic Assessment and Services project was to determine if it was possible to identify 1 or 2 ADHD criteria that could serve as "gate" criteria to screen for the disorder.
Psychiatric outpatients (N = 1,134) were evaluated using a semi-structured diagnostic interview for DSM-IV criteria of ADHD. We computed the sensitivity, specificity, and positive and negative predictive values of each of the 18 ADHD criteria to identify 1 or 2 criteria that could be used to screen for the disorder. We conducted a validation and cross-validation analysis by splitting the sample in half.
In both the validation and cross-validation samples, a 2-item screen of difficulty sustaining attention and fidgetiness had a sensitivity of >90%. The negative predictive value of the 2-item screen was >95%.
Clinicians can screen for ADHD in adults by inquiring about 2 features of the disorder (ie, difficulty sustaining attention and fidgetiness), the presence of which captures most patients with the disorder and the absence of which rules out the disorder.
注意力缺陷多动障碍(ADHD)是一种严重疾病,在成年人中常常未得到充分诊断。罗德岛改善诊断评估与服务方法项目的这份报告的目的是确定是否有可能识别出1条或2条ADHD标准,作为筛查该疾病的“门槛”标准。
对精神科门诊患者(N = 1134)使用针对ADHD的DSM-IV标准的半结构化诊断访谈进行评估。我们计算了18条ADHD标准中每条标准的敏感性、特异性以及阳性和阴性预测值,以识别出1条或2条可用于筛查该疾病的标准。我们通过将样本分成两半进行了验证和交叉验证分析。
在验证样本和交叉验证样本中,一个包含难以持续保持注意力和坐立不安这两项的筛查,其敏感性均大于90%。该两项筛查的阴性预测值大于95%。
临床医生可以通过询问该疾病的两个特征(即难以持续保持注意力和坐立不安)来筛查成年人中的ADHD,存在这两个特征可筛查出大多数患有该疾病的患者,而不存在则可排除该疾病。