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北京城区人群中代谢肥胖但体重正常(MONW)和代谢健康但肥胖(MHO)的流行情况。

Prevalence of metabolically obese but normal weight (MONW) and metabolically healthy but obese (MHO) in Chinese Beijing urban subjects.

机构信息

Department of VIP Medical Service, Beijing Hospital, National Center of Gerontology.

Department of Cardiology, Beijing Hospital, National Center of Gerontology.

出版信息

Biosci Trends. 2017 Sep 12;11(4):418-426. doi: 10.5582/bst.2017.01016. Epub 2017 Jul 24.

Abstract

The aim of this study was to assess the prevalence of metabolic syndrome (MetS) in non-obese adults (body mass index (BMI) < 25 kg/m) and the prevalence of obese adults (body mass index (BMI) ≥ 25 kg/m) without MetS in Chinese Beijing urban subjects. A cross-sectional study was conducted and the subjects who came to the hospital to receive a health examination were enrolled randomly. Regardless of age stratification, men have a higher prevalence of MetS than women. Among the urban Beijing population, prevalence of metabolically obese but normal weight (MONW) is lower than metabolically healthy but obese (MHO) regardless of gender. Except for the underweight group, participants exhibit significant differences between MetS and non-MetS subgroups in all tested variables in normal weight and overweight groups, whereas MONW and MHO participants exhibit significant differences in all variables except for creatinine (CR), aspartate aminotransferase (AST), uric acid (UAC) and high-density lipoprotein cholesterol (HDL-C). Women tend to have a higher MONW prevalence but lower MHO prevalence than men. Accordingly, MetS happens more frequently among those 40-59 yr. Besides, sex, age, WC, SBP, DBP, ALT, FG, UAC, TG, HDL-C and LDL-C are risk factors for MetS after multivariate adjustment. In conclusion, the prevalence of MONW is lower than MHO regardless of gender. Women tend to have a higher MONW prevalence but lower MHO prevalence than men.

摘要

本研究旨在评估非肥胖成年人(体重指数(BMI)<25kg/m)和无代谢综合征的肥胖成年人(体重指数(BMI)≥25kg/m)中代谢综合征(MetS)的患病率。进行了一项横断面研究,随机招募了前来医院进行健康检查的受试者。无论年龄分层如何,男性的 MetS 患病率均高于女性。在北京市城区人群中,无论性别如何,代谢肥胖但体重正常(MONW)的患病率均低于代谢健康但肥胖(MHO)。除体重过轻组外,在正常体重和超重组中,MetS 和非 MetS 亚组的所有测试变量之间均存在显著差异,而 MONW 和 MHO 参与者的除肌酐(CR)、天门冬氨酸氨基转移酶(AST)、尿酸(UAC)和高密度脂蛋白胆固醇(HDL-C)外,所有变量之间均存在显著差异。女性 MONW 患病率高于男性,但 MHO 患病率低于男性。因此,MetS 更常见于 40-59 岁人群。此外,经过多变量调整后,性别、年龄、WC、SBP、DBP、ALT、FG、UAC、TG、HDL-C 和 LDL-C 是 MetS 的危险因素。总之,无论性别如何,MONW 的患病率均低于 MHO。女性 MONW 患病率高于男性,但 MHO 患病率低于男性。

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