两名患有新生儿甲状腺毒症的 siblings 的促甲状腺素受体抗体和甲状腺功能测试
Thyroid-stimulating immunoglobulins and thyroid function tests in two siblings with neonatal thyrotoxicosis.
作者信息
Wit J M, Rees-Smith B, Creagh F M, Bruinse H W, van der Heide D, Docter R, Gerards L J
出版信息
Eur J Pediatr. 1986 Apr;145(1-2):143-7. doi: 10.1007/BF00441879.
Thyroid function and serum TSI levels in two siblings with neonatal thyrotoxicosis are described. The first infant was treated with exchange transfusion and potassium iodide. The second infant was treated with intrauterine propylthiouracil followed by potassium iodide. In contrast to the first infant, the second infant had no clinical sign of neonatal thyrotoxicosis. He also had lower TSI levels with a biological half-life of 5 days. Only one of three assays showed some TSI activity in breast milk.
描述了两名患有新生儿甲状腺毒症的兄弟姐妹的甲状腺功能和血清促甲状腺素受体抗体（TSI）水平。第一名婴儿接受了换血疗法和碘化钾治疗。第二名婴儿在子宫内接受丙硫氧嘧啶治疗，随后使用碘化钾。与第一名婴儿不同，第二名婴儿没有新生儿甲状腺毒症的临床症状。他的TSI水平也较低，生物半衰期为5天。三项检测中只有一项显示母乳中有一些TSI活性。
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