Thorarinsson Andri, Fröjd Victoria, Kölby Lars, Ljungdal Johan, Taft Charles, Mark Hans
Department of Plastic Surgery, Sahlgrenska University Hospital, University of Gothenburg, The Sahlgrenska Academy, Institute for Clinical Sciences, Gothenburg, Sweden; and University of Gothenburg, The Sahlgrenska Academy, Institute of Health and Care Sciences, Gothenburg, Sweden.
Plast Reconstr Surg Glob Open. 2017 Jun 21;5(6):e1316. doi: 10.1097/GOX.0000000000001316. eCollection 2017 Jun.
Studies have confirmed that breast reconstruction is beneficial to improve health-related quality of life (HR-QoL) in breast cancer patients. Our aim was to compare 4 different methods of breast reconstruction on patient satisfaction and HR-QoL using both general and specific patient-reported outcome instruments.
Retrospectively, 459 patients who underwent breast reconstruction with a deep inferior epigastric artery perforator (DIEP) flap, latissimus dorsi flap, lateral thoracodorsal flap, or expander with secondary implant and who had responded to the questionnaires were enrolled. Questionnaire answers, together with demographic and follow-up data, were statistically analyzed and compared between groups. Short-Form 36 Health Survey (SF-36) results were also compared with those from a sample of 930 age-matched women from the Swedish population.
There were slight differences in the SF-36 results but no significant differences in Psychological General Well-Being Index and EuroQoL-5 Dimension Questionnaire results between groups. Analysis of Breast-Q showed that the DIEP group had significantly higher score on the scale satisfaction with breast, significantly higher score in satisfaction with outcome than the lateral thoracodorsal flap ( = 0.014) and EXP groups ( = 0.024). There were no significant differences in most of the domains of the HR-QoL instruments. The higher satisfaction with breasts and outcome in the DIEP group is interesting, considering the higher complication rates associated with this reconstruction method.
Patients who underwent breast reconstruction with a DIEP flap were more satisfied with their reconstructed breast and outcome than the other 3 groups. Breast reconstruction centers should make DIEP reconstruction widely available to patients after mastectomy.
研究已证实乳房重建有助于改善乳腺癌患者与健康相关的生活质量(HR-QoL)。我们的目的是使用一般和特定的患者报告结局工具,比较4种不同的乳房重建方法对患者满意度和HR-QoL的影响。
回顾性纳入459例行乳房重建术的患者,这些患者采用腹壁下深动脉穿支(DIEP)皮瓣、背阔肌皮瓣、胸背外侧皮瓣或扩张器二期植入假体进行乳房重建,且对问卷作出了回应。对问卷答案以及人口统计学和随访数据进行统计分析并在组间进行比较。还将36项简短健康调查(SF-36)结果与来自瑞典人群的930名年龄匹配女性样本的结果进行比较。
组间SF-36结果存在细微差异,但心理总体幸福感指数和欧洲五维健康量表问卷结果无显著差异。乳房-Q分析显示,DIEP组在乳房满意度量表上得分显著更高,在结局满意度方面得分显著高于胸背外侧皮瓣组(P = 0.014)和扩张器二期植入假体组(P = 0.024)。HR-QoL工具的大多数领域无显著差异。考虑到这种重建方法相关的并发症发生率较高,DIEP组对乳房和结局的较高满意度很有意思。
与其他3组相比,接受DIEP皮瓣乳房重建的患者对其重建乳房和结局更满意。乳房重建中心应使DIEP重建术在乳房切除术后的患者中广泛可用。