Seffer Istvan, Nemeth Zoltan
Human Cellular Therapy Laboratory, Seffer Clinic, Budapest, Hungary.
Plast Reconstr Surg Glob Open. 2017 Jun 29;5(6):e1376. doi: 10.1097/GOX.0000000000001376. eCollection 2017 Jun.
Peripheral blood mononuclear cells (PBMCs) are multipotent, and plasma contains growth factors involving tissue regeneration. We hypothesized that transplantation of PBMC-plasma will promote the recovery of paralyzed facial muscles in Bell palsy. This case report describes the effects of PBMC-plasma transplantations in a 27-year-old female patient with right side Bell palsy. On the affected side of the face, the treatment resulted in both morphological and functional recovery including voluntary facial movements. These findings suggest that PBMC-plasma has the capacity of facial muscle regeneration and provides a promising treatment strategy for patients suffering from Bell palsy or other neuromuscular disorders.
外周血单个核细胞（PBMCs）具有多能性，血浆中含有参与组织再生的生长因子。我们推测，PBMC-血浆移植将促进贝尔面瘫患者瘫痪面部肌肉的恢复。本病例报告描述了PBMC-血浆移植对一名27岁右侧贝尔面瘫女性患者的影响。在面部患侧，该治疗导致了包括自主面部运动在内的形态和功能恢复。这些发现表明，PBMC-血浆具有面部肌肉再生能力，为贝尔面瘫或其他神经肌肉疾病患者提供了一种有前景的治疗策略。
