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瑞典牙周炎患者中与年龄相关的患病率及特征 。 (你提供的原文“Age-related prevalence and characteristics of in periodontitis patients living in Sweden.”似乎不完整,这里的“of ”后面缺少具体内容。)

Age-related prevalence and characteristics of in periodontitis patients living in Sweden.

作者信息

Claesson Rolf, Höglund-Åberg Carola, Haubek Dorte, Johansson Anders

机构信息

Division of Oral Microbiology, Department of Odontology, Umeå University, Umeå, Sweden.

Division of Molecular Periodontology, Department of Odontology, Umeå University, Umeå, Sweden.

出版信息

J Oral Microbiol. 2017 Jun 20;9(1):1334504. doi: 10.1080/20002297.2017.1334504. eCollection 2017.

Abstract

: The presence of in patients with periodontitis has been extensively studied for decades. : To study the prevalence of in younger and older periodontitis patients and to genetically characterize isolates of this bacterium. : Data from microbiological analyses of 3459 subgingival plaque samples collected from 1445 patients, 337 'younger' patients (≤35 yrs) and 1108 'older' patients (>35 yrs) during 15 years (2000-2014), has been summerized. Isolates of were serotyped, leukotoxin promoter typed (JP2 and non JP2) and arbitrarily primed PCR (AP-PCR) genotyped. The origin of the JP2 genotype detected in the study population was determined. : The prevalence of was higher among younger than older patients and samples from the younger patients contained higher proportions of the bacterium. Serotype b was more prevalent among younger patients and the majorty of these isolates was from the same AP-PCR genotype. The JP2 genotype was detected in 1.2% of the patients, and the majority of these carriers were of non-African origin. : For presence and charcteristics of in clinical samples the age of the carriers were a discriminating factor. Additional, apparently non-African carriers of the JP2 genotype of were identified.

摘要

几十年来,牙周炎患者中[某种细菌]的存在情况已得到广泛研究。:研究[该细菌]在年轻和老年牙周炎患者中的患病率,并对该细菌的分离株进行基因特征分析。:总结了在15年(2000 - 2014年)期间从1445名患者(337名“年轻”患者(≤35岁)和1108名“老年”患者(>35岁))收集的3459份龈下菌斑样本的微生物分析数据。对[该细菌]的分离株进行血清分型、白细胞毒素启动子分型(JP2和非JP2)以及任意引物PCR(AP-PCR)基因分型。确定了在研究人群中检测到的JP2基因型的来源。:[该细菌]在年轻患者中的患病率高于老年患者,并且来自年轻患者的样本中该细菌的比例更高。血清型b在年轻患者中更普遍,并且这些分离株中的大多数来自相同的AP-PCR基因型。在1.2%的患者中检测到JP2基因型,并且这些携带者中的大多数是非非洲裔。:对于临床样本中[该细菌]的存在和特征,携带者的年龄是一个区分因素。此外,还鉴定出了[该细菌]JP2基因型的明显非非洲携带者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ce0/5508378/4c2e9bd50af3/zjom_a_1334504_f0001_b.jpg

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