Rua Monsenhor Furtado s/n, Bairro Rodolfo Teófilo, Fortaleza, Ceará, CEP 60430-170, Brazil,
Med Oral Patol Oral Cir Bucal. 2014 Mar 1;19(2):e184-91. doi: 10.4317/medoral.19304.
Several studies have focused on the relationship among serotype distribution, ethnical status and geographic populations, and periodontal conditions. Studies that have investigated the prevalence and the distribution of A. actinomycetemcomitans serotypes and the relation between the different serotypes of the bacterium and periodontal status were reviewed.
A systematic literature search for publications regarding the distribution of A. actinomycetemcomitans serotypes in subgingival samples of periodontitis patients and periodontally healthy subjects by employing polymerase chain reaction (PCR) was conducted.
From the 85 studies identified in the first analysis, only 12 met all inclusion and exclusion criteria. Clinical isolates from diverse geographic populations with different periodontal conditions were evaluated. Serotypes a, b and c were largely found, and serotype c was the most prevalent. They were isolated from various periodontal conditions, including aggressive periodontitis.
The available literature suggests that serotypes a, b, and c are globally dominant, serotypes d and e are rare, and the prevalence of the most recently identified serotype f is still unknown. It is widely accepted that distribution patterns of A. actinomycetemcomitans vary among subjects of different ethnicity and geographic regions. The correlation of different serotypes with various periodontal conditions remains unclear.
多项研究集中于血清型分布、种族状况和地理人群，以及牙周状况之间的关系。综述了研究侵袭性牙周炎患者和牙周健康个体龈下样本中伴放线放线杆菌血清型的流行情况及其与不同血清型细菌之间的关系。
采用聚合酶链反应（PCR）对关于伴放线放线杆菌血清型在侵袭性牙周炎患者和牙周健康个体龈下样本中分布的文献进行了系统的文献检索。
在第一次分析中，从 85 项研究中仅确定了 12 项符合所有纳入和排除标准。对具有不同牙周状况的不同地理人群的临床分离株进行了评估。主要发现血清型 a、b 和 c，其中血清型 c 最为常见。它们从各种牙周状况中分离出来，包括侵袭性牙周炎。
现有文献表明，血清型 a、b 和 c 在全球范围内占主导地位，血清型 d 和 e 较为罕见，最近发现的血清型 f 的流行情况仍不清楚。普遍认为，伴放线放线杆菌的分布模式在不同种族和地理区域的人群中存在差异。不同血清型与各种牙周状况的相关性尚不清楚。
