Müller Helge H O, Reike Mareen, Grosse-Holz Simon, Röther Mareike, Lücke Caroline, Philipsen Alexandra, Kornhuber Johannes, Grömer Teja W
Department of Psychiatry and Psychotherapy, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen.
Department of Psychiatry and Psychotherapy, Medical Campus University of Oldenburg, School of Medicine and Health Sciences, University Hospital Karl-Jaspers-Klinik, Bad Zwischenahn, Germany.
Ment Illn. 2017 Jun 28;9(1):7093. doi: 10.4081/mi.2017.7093. eCollection 2017 Mar 22.
Electroconvulsive therapy (ECT) is effective in the treatment of treatment-resistant major depression. The fear of cognitive impairment after ECT often deters patients from choosing this treatment option. There is little reliable information regarding the effects of ECT on overall cognitive performance, while short-term memory deficits are well known but not easy to measure within clinical routines. In this pilot study, we examined ECT recipients' pre- and post-treatment performances on a digital ascending number tapping test. We found that cognitive performance measures exhibited good reproducibility in individual patients and that ECT did not significantly alter cognitive performance up to 2 hours after this therapy was applied. Our results can help patients and physicians make decisions regarding the administration of ECT. Digital measurements are recommended, especially when screening for the most common side effects on cognitive performance and short-term memory.
电休克疗法(ECT)在治疗难治性重度抑郁症方面是有效的。对ECT后认知障碍的恐惧常常使患者不愿选择这种治疗方案。关于ECT对整体认知表现的影响,几乎没有可靠的信息,而短期记忆缺陷是众所周知的,但在临床常规中不易测量。在这项初步研究中,我们检查了接受ECT治疗的患者在数字递增数字敲击测试中的治疗前和治疗后的表现。我们发现,认知表现测量在个体患者中具有良好的可重复性,并且在应用该疗法后长达2小时内,ECT并未显著改变认知表现。我们的结果可以帮助患者和医生就ECT的施用做出决策。建议进行数字测量,尤其是在筛查对认知表现和短期记忆最常见的副作用时。