Comprehensive Heart Failure Centre Würzburg and Department of Internal Medicine I, University and University Hospital Würzburg, Würzburg, Germany.
Deutsches Zentrum für Herzinsuffizienz Würzburg, Am Schwarzenberg 15, 97078, Würzburg, Germany.
Clin Res Cardiol. 2017 Nov;106(11):913-922. doi: 10.1007/s00392-017-1137-7. Epub 2017 Jul 26.
Chronic heart failure (HF) is associated with significant healthcare expenditure, morbidity, and mortality. This study investigated the epidemiology of HF in Germany.
This retrospective study used anonymous healthcare claims data from the German Health Risk Institute on individuals with statutory health insurance. Patients with uninterrupted data from 1 January 2009 to 31 December 2013 or death (whichever occurred first), and ≥2 recorded HF-related diagnoses in 2011, were included. Patients with newly diagnosed HF were identified. Patients were followed up for 2 years from first diagnosis.
Of 3,132,337 eligible patients, 123,925 (55.0% women; mean age 76.2 years) had HF: a prevalence of 3.96%. Of these, 26,368 had newly diagnosed HF: an incidence of 655/100,000 persons at risk. Incidence increased with age and was similar regardless of sex. During follow-up, there were 48,159 hospital admissions among newly diagnosed patients (1.8 hospitalizations/patient/2 years); HF accounted for 6% of these. Additionally, 20,148 patients (16.3%) overall and 5983 newly diagnosed patients (22.7%) died. Most new cases of HF were diagnosed by office-based physicians (63.2%); new cases among hospital inpatients were predominantly diagnosed by internal medicine specialists (70.7%). Overall, 94.0% received their initial prescription for HF treatment from a family practitioner.
The high prevalence and incidence observed in this representative sample emphasize the burden of HF in Germany. Substantial hospitalization rates and mortality highlight the need for early diagnosis and appropriate treatment, and for close cooperation between physician specialties and healthcare sectors.
慢性心力衰竭(HF)与大量医疗支出、发病率和死亡率有关。本研究调查了德国 HF 的流行病学情况。
这是一项回顾性研究,使用了德国健康风险研究所的匿名医疗索赔数据,该数据来自参加法定健康保险的个人。研究纳入了自 2009 年 1 月 1 日至 2013 年 12 月 31 日期间数据完整或先于该日期死亡(以先发生者为准),且在 2011 年至少有 2 次 HF 相关诊断记录的患者。新发 HF 患者的诊断被确定。从首次诊断起对患者进行为期 2 年的随访。
在 3132337 名符合条件的患者中,有 123925 名(55.0%为女性;平均年龄 76.2 岁)患有 HF:患病率为 3.96%。其中,有 26368 名患者为新发 HF:发病率为 655/100000 人年。发病率随年龄增长而增加,且无论性别如何均相似。在随访期间,新发患者中有 48159 人次住院(1.8 次住院/患者/2 年);HF 占这些住院的 6%。此外,共有 20148 名(16.3%)患者和 5983 名新发患者(22.7%)死亡。大多数新诊断的 HF 是由门诊医生诊断的(63.2%);住院患者中,新诊断的 HF 主要由内科医生诊断(70.7%)。总体而言,94.0%的患者首次接受 HF 治疗处方是由家庭医生开具的。
在这个代表性样本中观察到的 HF 高患病率和发病率强调了德国 HF 的负担。高住院率和死亡率突出表明需要早期诊断和适当治疗,以及医生专业和医疗保健部门之间的密切合作。