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甲型H1N1流感疫苗诱发的乳-碱综合征

Milk-Alkali syndrome induced by H1N1 influenza vaccine.

作者信息

Al-Hwiesh Abdullah K, Abdul-Rahman Ibrahiem Saeed, Al-Oudah Nadia, Al-Solami Sana, Al-Muhanna Fahd A

机构信息

Department of Internal Medicine, Division of Nephrology, King Fahd Hospital of the University, Al-Khobar, Saudi Arabia.

出版信息

Saudi J Kidney Dis Transpl. 2017 Jul-Aug;28(4):912-915.

Abstract

Milk-Alkali syndrome (MAS) consists of a triad of hypercalcemia, metabolic alkalosis, and acute renal failure. We hereby report a 75-year-old Indian gentleman who presented to our emergency department with a history of generalized weakness and easy fatigability. Investigations were consistent with MAS secondary to calcium carbonate and calcitriol treatment to prevent osteoporosis, aggravated by H1N1 influenza vaccine. The patient was treated with hemodialysis and zoledronate. To our knowledge, this is the first reported case of such association in the literature.

摘要

乳碱综合征(MAS)由高钙血症、代谢性碱中毒和急性肾衰竭三联征组成。我们在此报告一名75岁的印度男性,他因全身无力和易疲劳的病史前来我院急诊科就诊。检查结果与因碳酸钙和骨化三醇治疗预防骨质疏松继发的MAS相符,甲型H1N1流感疫苗加重了病情。该患者接受了血液透析和唑来膦酸治疗。据我们所知,这是文献中首次报道的此类关联病例。

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