一种非血红素、高自旋的 {FeNO} 配合物，可自发生成 NO。
A Nonheme, High-Spin {FeNO} Complex that Spontaneously Generates NO.
机构信息
Department of Chemistry, Johns Hopkins University , Baltimore, Maryland 21218, United States.
Institute of Environmental Health, Oregon Health & Science University , Portland, Oregon 97239, United States.
出版信息
J Am Chem Soc. 2017 Aug 9;139(31):10621-10624. doi: 10.1021/jacs.7b05549. Epub 2017 Jul 27.
Abstract
One-electron reduction of [Fe(NO)-(N3PyS)]BF (1) leads to the production of the metastable nonheme {FeNO} complex, [Fe(NO)(N3PyS)] (3). Complex 3 is a rare example of a high-spin (S = 1) {FeNO} and is the first example, to our knowledge, of a mononuclear nonheme {FeNO} species that generates NO. A second, novel route to 3 involves addition of Piloty's acid, an HNO donor, to an Fe precursor. This work provides possible new insights regarding the mechanism of nitric oxide reductases.
摘要
一电子还原 [Fe(NO)-(N3PyS)]BF（1）生成亚稳态非血红素 {FeNO} 配合物 [Fe(NO)(N3PyS)]（3）。配合物 3 是一个罕见的高自旋 (S = 1) {FeNO} 的例子，也是我们所知的第一个产生 NO 的单核非血红素 {FeNO} 物种的例子。第二条生成 3 的新途径涉及到将 Piloty 酸（一种 HNO 供体）添加到铁前体中。这项工作为一氧化氮还原酶的机制提供了新的见解。
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