Cell Biology Program, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
Semin Cell Dev Biol. 2018 Aug;80:13-16. doi: 10.1016/j.semcdb.2017.07.038. Epub 2017 Jul 24.
Evidence emerges that redox gradients regulate morphogenesis, inflammation, regeneration, and healing of tissues. At the example of redox signaling during the zebrafish wound response, I briefly discuss current ideas on how such patterns might be sensed and spatially regulated to guide physiological processes over distances in animals.
有证据表明氧化还原梯度调节组织的形态发生、炎症、再生和愈合。以斑马鱼伤口反应中的氧化还原信号为例,我简要讨论了目前关于这些模式如何被感知和空间调节以引导动物体内远距离生理过程的想法。