Roberts R J, Rowe R C
J Pharm Pharmacol. 1986 Jul;38(7):526-8. doi: 10.1111/j.2042-7158.1986.tb04628.x.
The brittle fracture propensity test which was originally designed for large, square compacts with a central hole has been modified and extended to compacts of 'tablet-sized' dimensions. This allows a brittle fracture propensity (BFP) index to be measured at strain rates and conditions approaching those normally used in tableting. The BFP indices for microcrystalline cellulose, Tablettose and heavy magnesium carbonate were evaluated at punch velocities of 3.33 and 200 mm s-1 and found to be in good agreement with the results of previous workers.
最初为带有中心孔的大型方形压块设计的脆性断裂倾向测试已被修改并扩展到“片剂尺寸”的压块。这使得能够在接近压片通常使用的应变率和条件下测量脆性断裂倾向（BFP）指数。在3.33和200毫米/秒的冲头速度下评估了微晶纤维素、Tablettose和重质碳酸镁的BFP指数，发现与先前研究人员的结果高度一致。
