减肥手术对肥胖及代谢指标的影响：中东患者的一项前瞻性队列研究
Effect of bariatric surgery on adiposity and metabolic profiles: A prospective cohort study in Middle-Eastern patients.
作者信息
Mazidi Mohsen, Rezaie Peyman, Jangjoo Ali, Tavassoli Alireza, Rajabi Mohammad Taghi, Kengne Andre Pascal, Nematy Mohsen
机构信息
Mohsen Mazidi, Key State Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100049, China.
出版信息
World J Diabetes. 2017 Jul 15;8(7):374-380. doi: 10.4239/wjd.v8.i7.374.
AIM
To investigate changes in adiposity and cardio-metabolic risk profile following Roux-en-Y gastric bypass in patients of Middle Eastern ethnicity with severe obesity.
METHODS
This prospective cohort study involved 92 patients who met the indications of bariatric surgery. Post-procedure markers of obesity and cardiometabolic profile were monitored regularly for a year.
RESULTS
Mean body mass index decreased by 29.5% from 41.9 to 29.5 kg/m between baseline and 12-mo follow-up, while mean fat mass decreased by 45.9% from 64.2 kg to 34.7 kg. An improvement was also observed in the gluco-metabolic profile with both fasting glucose and HbA1c substantially decreasing ( < 0.001).
CONCLUSION
The present study shows the short to medium term (1 year) health benefits of bariatric surgery for patients of Middle Eastern ethnicity.
目的
研究中东裔重度肥胖患者接受Roux-en-Y胃旁路手术后肥胖及心血管代谢风险状况的变化。
方法
这项前瞻性队列研究纳入了92例符合减肥手术指征的患者。术后定期监测肥胖及心血管代谢指标，为期一年。
结果
从基线到12个月随访期间，平均体重指数从41.9降至29.5kg/m²，下降了29.5%，平均脂肪量从64.2kg降至34.7kg，下降了45.9%。糖代谢指标也有所改善，空腹血糖和糖化血红蛋白均大幅下降（<0.001）。
结论
本研究显示了减肥手术对中东裔患者的短期至中期（1年）健康益处。
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