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强脉冲光与脉冲染料激光治疗面部红斑的对比研究:一项半脸对照研究

IPL vs PDL in treatment of facial erythema: A split-face study.

作者信息

Handler Marc Z, Bloom Bradley S, Goldberg David J

机构信息

Skin Laser & Surgery Specialists of NY and NJ, New York, NY, USA.

Dermatology, Rutgers University New Jersey Medical School, Newark, NJ, USA.

出版信息

J Cosmet Dermatol. 2017 Dec;16(4):450-453. doi: 10.1111/jocd.12365. Epub 2017 Jul 27.

DOI:10.1111/jocd.12365
PMID:28752575
Abstract

BACKGROUND

Lasers and noncoherent intense pulse light sources effectively treat vascular lesions. Intense pulsed light (IPL), a nonablative treatment for photorejuvenation, uses a flashlamp which emits noncoherent light between 400 and 1400 nm. The light may be filtered to target a specific chromophore. The pulsed dye laser (PDL), at 595 nm, has been the historical standard of care in the treatment of facial erythema. We sought to determine whether IPL may be used in lieu of PDL in reducing facial erythema.

OBJECTIVES

To determine whether IPL may be used to treat facial erythema with equal efficacy as PDL used at nonpurpuric settings.

METHODS

Prospective investigation of a cohort of 15 subjects with unwanted bilateral facial erythema. Subjects presented for two treatments with an IPL (BBL™ BroadBand Light; Sciton, Palo Alto, CA) to one half of the face and PDL (Cynergy™; Cynosure, Westford, MA) to the other half.

RESULTS

Patients with facial erythema may be successfully treated with IPL or PDL.

CONCLUSIONS

Intense pulsed light and pulsed dye laser with nonpurpuric settings were equally effective in reducing facial erythema.

摘要

背景

激光和非相干强脉冲光源可有效治疗血管性病变。强脉冲光(IPL)是一种用于皮肤光老化的非剥脱性治疗方法,它使用闪光灯发射400至1400纳米之间的非相干光。该光可经过滤以靶向特定的发色团。波长为595纳米的脉冲染料激光(PDL)一直是治疗面部红斑的历史标准治疗方法。我们试图确定IPL是否可替代PDL用于减轻面部红斑。

目的

确定IPL是否可用于治疗面部红斑,其疗效与非紫癜性设置下使用的PDL相同。

方法

对15名患有双侧面部不必要红斑的受试者进行前瞻性研究。受试者接受两次治疗,一侧面部使用IPL(BBL™ 宽带光;Sciton公司,加利福尼亚州帕洛阿尔托),另一侧面部使用PDL(Cynergy™;Cynosure公司,马萨诸塞州韦斯特福德)。

结果

面部红斑患者使用IPL或PDL均可成功治疗。

结论

非紫癜性设置下的强脉冲光和脉冲染料激光在减轻面部红斑方面同样有效。

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