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非侵入性嫩肤新见解:罗丹明强脉冲光系统的作用

New Insight in Noninvasive Rejuvenation: The Role of a Rhodamine-Intense Pulsed Light System.

作者信息

Cannarozzo Giovanni, Bonciani Diletta, Tamburi Federica, Mazzilli Sara, Garofalo Virginia, Del Duca Ester, Sannino Mario, Zingoni Tiziano, Nisticò Steven Paul

机构信息

Dermatology Unit, University Polyclinic, Tor Vergata, Rome, Italy.

Department of Dermatology, University of Florence, Florence, Italy.

出版信息

Photobiomodul Photomed Laser Surg. 2019 Sep;37(9):539-543. doi: 10.1089/photob.2019.4626. Epub 2019 Aug 5.

Abstract

Rhodamine-intense pulsed light (r-IPL) is a noncoherent, noncollimated, polychromatic light energy optimized for a double-peak wavelength emission, ranging between 550-680 and 850-1200 nm. Traditional IPL works within visible and infrared spectra, targeting hemoglobin and melanin, are effective to treat rosacea and pigmentary disorders. r-IPL, a new technology in dermatology, emits high-intensity light with a wavelength peak similar to the one of the pulsed dye lasers, showing a good safety and efficacy profile in nonablative photorejuvenation. Assess efficacy and safety of r-IPL on photodamaged facial skin showing hyperpigmentation, telangiectasias, fine lines, and textural changes. Five sessions of r-IPL treatment (fluence ranged between 13.5 and 14 J/cm) have been performed on one 75-year-old lady affected by facial photodamaged skin. Efficacy of treatment was evaluated using the Fitzpatrick Elastosis and Wrinkles Scale (FEWS) and the Global Aesthetic Improvement (GAI) Scale assessed by an investigator, compared with baseline. Treatment safety and tolerance were also evaluated using the Visual Analog Scale (VAS). Photographic and multispectral evaluation demonstrated relevant improvement (vascular, pigment, and texture) of photodamaged facial skin. One month after the last treatment, significant improvement in facial wrinkle and texture was noted. FEWS scores decreased significantly from 7 to 2. According to the GAI scale, the patient had an improvement in skin texture. Immediate response included mild-to-moderate erythema and only trace-mild edema in the treatment area. Pain during the treatment was minimal with a mean VAS pain score of 3/10. No other adverse events were reported. No post-treatment downtime was recorded. r-IPL may represent a valid therapeutic approach in noninvasive photorejuvenation.

摘要

罗丹明强脉冲光(r-IPL)是一种非相干、非准直的多色光能,其双峰值波长发射经过优化,范围在550 - 680纳米和850 - 1200纳米之间。传统的强脉冲光在可见光和红外光谱范围内起作用,以血红蛋白和黑色素为靶点,对治疗酒渣鼻和色素沉着性疾病有效。r-IPL是皮肤科的一项新技术,发射高强度光,其波长峰值与脉冲染料激光的波长峰值相似,在非剥脱性光嫩肤方面显示出良好的安全性和有效性。评估r-IPL对出现色素沉着、毛细血管扩张、细纹和质地变化的光损伤面部皮肤的疗效和安全性。对一名75岁面部光损伤皮肤的女性进行了五次r-IPL治疗(能量密度范围为13.5至14 J/cm²)。由一名研究者使用Fitzpatrick弹性组织变性和皱纹量表(FEWS)以及全球美学改善(GAI)量表,与基线相比评估治疗效果。还使用视觉模拟量表(VAS)评估治疗的安全性和耐受性。摄影和多光谱评估显示光损伤面部皮肤有显著改善(血管、色素和质地方面)。最后一次治疗后一个月,面部皱纹和质地有显著改善。FEWS评分从7显著降至2。根据GAI量表,患者的皮肤质地有改善。即时反应包括治疗区域出现轻度至中度红斑,仅伴有微量至轻度水肿。治疗期间疼痛轻微,平均VAS疼痛评分为3/10。未报告其他不良事件。未记录治疗后的停工期。r-IPL可能是非侵入性光嫩肤的一种有效治疗方法。

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