耐甲氧西林中间型葡萄球菌分离株对牛磺罗定的敏感性
Taurolidine susceptibility of methicillin-resistant Staphylococcus pseudintermedius isolates.
作者信息
Wormhoudt Tiffany, Séguin Bernard, Bemis David A, Hyatt Doreene
机构信息
Departments of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO (Wormhoudt, Séguin).
Microbiology, Immunology, and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO (Hyatt).
出版信息
J Vet Diagn Invest. 2017 Nov;29(6):910-911. doi: 10.1177/1040638717723043. Epub 2017 Jul 28.
Infections caused by methicillin-resistant Staphylococcus pseudintermedius (MRSP) can be challenging to treat because they are often resistant to many other antimicrobial agents. We assessed the susceptibility of 29 MRSP isolates from dogs to taurolidine in vitro. There was no growth at 0.12% taurolidine and light growth at 0.06% for all isolates. Taurolidine was reliable at inhibiting growth of MRSP at a concentration of 1,200 µg/mL.
耐甲氧西林中间型葡萄球菌（MRSP）引起的感染治疗起来可能具有挑战性，因为它们通常对许多其他抗菌药物耐药。我们在体外评估了29株来自犬的MRSP分离株对牛磺罗定的敏感性。所有分离株在0.12%牛磺罗定浓度下均无生长，在0.06%浓度下有轻微生长。牛磺罗定在浓度为1200 µg/mL时能可靠地抑制MRSP的生长。
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