Kulas Anthony S, Schmitz Randy J, Shultz Sandra J, Waxman Justin P, Wang Hsin-Min, Kraft Robert A, Partington Heath S
East Carolina University, Greenville, North Carolina.
The University of North Carolina at Greensboro, Greensboro, North Carolina.
J Orthop Res. 2018 Mar;36(3):963-970. doi: 10.1002/jor.23664. Epub 2017 Aug 11.
Determining the magnitude of quadriceps and hamstring muscle volume asymmetries in healthy individuals is a critical first step toward interpreting asymmetries as compensatory or abnormal in pathological populations. The purpose of this study was to determine the magnitude of whole and individual muscle volume asymmetries, quantified as right-left volume differences, for the quadriceps and hamstring muscles in a young and healthy population. Twenty-one healthy individuals participated: Eleven females age = 22.6 ± 2.9 years and 10 males age = 23.2 ± 3.4 years. Whole muscle group and individual muscle volume asymmetries were quantified within the context of absolute measurement error using a 95% Limits of Agreement approach. Mean muscle asymmetries ranged from -3.0 to 6.0% for all individual and whole muscle groups. Whole muscle group 95% limits of agreements represented ±11.4% and ±8.8% volume asymmetries for the hamstrings and quadriceps, respectively. Individual muscle asymmetry 95% limits of agreements ranged from ∼ ± 11-13% for the vastii muscles while the biceps femoris short-head (±33.5%), long-head (±20.9%), and the rectus femoris (±21.4%) displayed the highest relative individual asymmetries. Individual muscle asymmetries exceeded absolute measurement error in 70% of all cases, with 26% of all cases exceeding 10% asymmetry. Although whole muscle group asymmetries appear to be near the 10% assumed clinical threshold of normality, the greater magnitude of individual muscle asymmetries highlights the subject- and muscle-specific variability in volume asymmetry. Future research is warranted to determine if volume asymmetry thresholds exist that discriminate between healthy and pathological populations. Statement of Clinical Significance: Muscle volume asymmetries displayed in healthy individuals provide a reference for interpreting asymmetries in pathological populations. © 2017 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 36:963-970, 2018.
确定健康个体股四头肌和腘绳肌体积不对称的程度，是将不对称现象解释为病理人群中的代偿性或异常情况的关键第一步。本研究的目的是确定年轻健康人群中股四头肌和腘绳肌整体及单个肌肉体积不对称的程度，以左右体积差异进行量化。21名健康个体参与了研究：11名女性，年龄为22.6±2.9岁；10名男性，年龄为23.2±3.4岁。使用95%一致性界限方法，在绝对测量误差范围内对整个肌肉群和单个肌肉体积不对称进行量化。所有单个和整个肌肉群的平均肌肉不对称范围为-3.0%至6.0%。整个肌肉群的95%一致性界限分别表示腘绳肌和股四头肌的体积不对称率为±11.4%和±8.8%。股直肌的单个肌肉不对称95%一致性界限范围约为±11%-13%，而股二头肌短头（±33.5%）、长头（±20.9%）和股直肌（±21.4%）表现出最高的相对个体不对称性。在所有病例中，70%的单个肌肉不对称超过了绝对测量误差，26%的病例不对称超过10%。尽管整个肌肉群的不对称似乎接近假定的10%正常临床阈值，但单个肌肉不对称的更大程度突出了体积不对称中个体和肌肉特异性的变异性。有必要进行未来研究以确定是否存在区分健康和病理人群的体积不对称阈值。临床意义声明：健康个体中显示的肌肉体积不对称可为解释病理人群中的不对称提供参考。©2017骨科研究协会。由Wiley Periodicals, Inc.出版。《矫形外科研究杂志》36:963-970, 2018。
