Office management of anaphylaxis.

The primary therapy for anaphylaxis is epinephrine, which should be stocked in the office in the appropriate dilution (1:1,000). Antihistamines and corticosteroids are useful adjunctive agents that may be given in the office. Patients with progressive or severe symptoms should be transferred immediately to a facility where monitoring is available and vasopressors can be administered. Various measures can be taken to prevent anaphylaxis or limit its severity.